Evidence map›Paper›PMID 26401044›Full record

ArticleJournal of virology2015

Replication-Competent Influenza B Reporter Viruses as Tools for Screening Antivirals and Antibodies.

Benjamin O Fulton, Peter Palese, Nicholas S Heaton

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Benjamin O FultonDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Peter PaleseDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Nicholas S HeatonDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA nicholas.heaton@duke.edu.
Icahn School of Medicine at Mount Sinai · US

Funding

Toward a Universal Influenza Virus VaccineP01AI097092 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI AHMED, RAFI · 2012 to 2022
$17.6M
NIAID NIH HHS HHSN272201400008CNIAID NIH HHS P01 AI097092NIAID NIH HHS P01AI097092-04PHS HHS HHSN272201400008C
6 · The paper itself

Abstract

Influenza B virus is a human pathogen responsible for significant health and economic burden. Research into this pathogen has been limited by the lack of reporter viruses. Here we describe the development of both a replication-competent fluorescent influenza B reporter virus and bioluminescent influenza B reporter virus. Furthermore, we demonstrate these reporter viruses can be used to quickly monitor viral growth and permit the rapid screening of antiviral compounds and neutralizing antibodies.

Indexed as

AnimalsDogsDrug Evaluation, PreclinicalFlow CytometryGenes, ReporterInfluenza B virusLuminescent ProteinsMadin Darby Canine Kidney CellsMicroscopy, FluorescenceVirus ReplicationLuminescent Proteins

Identifiers

PMID26401044
PMCPMC4645317
OpenAlexW1778254314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.