ArticleCerebral cortex (New York, N.Y. : 1991)2016
Multiple Causal Links Between Magnocellular-Dorsal Pathway Deficit and Developmental Dyslexia.
Article in Cerebral cortex (New York, N.Y. : 1991), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
81 citing papers in PubMed, 2 syntheses or guidelines pooled it, 199 citations in OpenAlex.
- Visual and Oculomotor Function in Developmental Dyslexia: A Systematic Review and Meta-Analysis.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Pooled it
- Dyslexia treatment studies: A systematic review and suggestions on testing treatment efficacy with small effects and small samples.Behavior research methods · 2021Pooled it
- A new effective treatment for dyslexia based on dorsal visual stream neuromodulation.Journal of neurodevelopmental disorders · 2026Trial
- The effect of online visual games on visual perception, oculomotor, and balance skills of children with developmental dyslexia during the COVID-19 pandemic.International ophthalmology · 2023Trial
- Action video game training improves text reading accuracy, rate and comprehension in children with dyslexia: a randomized controlled trial.Scientific reports · 2021Trial
- Movement detection thresholds reveal proprioceptive impairments in developmental dyslexia.Scientific reports · 2021Trial
- Improving sentence reading performance in Chinese children with developmental dyslexia by training based on visual attention span.Scientific reports · 2019Trial
- Probing the use of visual search as a tool to enhance reading speed.Attention, perception & psychophysics · 2026Article
- Motion perception and eye movements predict reading readiness: Evidence from pre-readers in an action video game task.iScience · 2026Article
- Associations between READ1 deletion, reading proficiency, and white matter network organisation in children with and without developmental dyslexia.Brain structure & function · 2026Article
- Visual processing is a language-agnostic window into heterogeneity in early reading development.Current biology : CB · 2026Article
- Neural compensation through dorsal stream involvement in visual word recognition under perceptual degradation in a transparent language: evidence from fMRI.Behavioral and brain functions : BBF · 2026Article
- Developmental trajectories of visual temporal integration and segregation in children with and without developmental dyslexia.The British journal of developmental psychology · 2026Article
- Neural Mechanisms Underlying Reading Impairment in Children Learning a Second Language: A Review.Behavioral sciences (Basel, Switzerland) · 2025Review
- Multimodal investigation of the neurocognitive deficits underlying dyslexia in adulthood.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Effects of central vs. peripheral attentional-oculomotor exercise on lexical processing.Quarterly journal of experimental psychology (2006) · 2025Article
- Mediational effects of reading-related intermediate phenotypes from polygenic scores to reading skills.NPJ science of learning · 2025Article
- Flickering lenses enhance reading performance through placebo effect.Psychological research · 2025Article
- PLFest: A New Platform for Accessible, Reproducible, and Open Perceptual Learning Research.Journal of cognitive enhancement : towards the integration of theory and practice · 2024Article
- Evaluating correlations between reading ability and psychophysical measurements of dynamic visual information processing in Japanese adults.Scientific reports · 2024Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Although impaired auditory-phonological processing is the most popular explanation of developmental dyslexia (DD), the literature shows that the combination of several causes rather than a single factor contributes to DD. Functioning of the visual magnocellular-dorsal (MD) pathway, which plays a key role in motion perception, is a much debated, but heavily suspected factor contributing to DD. Here, we employ a comprehensive approach that incorporates all the accepted methods required to test the relationship between the MD pathway dysfunction and DD. The results of 4 experiments show that (1) Motion perception is impaired in children with dyslexia in comparison both with age-match and with reading-level controls; (2) pre-reading visual motion perception-independently from auditory-phonological skill-predicts future reading development, and (3) targeted MD trainings-not involving any auditory-phonological stimulation-leads to improved reading skill in children and adults with DD. Our findings demonstrate, for the first time, a causal relationship between MD deficits and DD, virtually closing a 30-year long debate. Since MD dysfunction can be diagnosed much earlier than reading and language disorders, our findings pave the way for low resource-intensive, early prevention programs that could drastically reduce the incidence of DD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.