Evidence map›Paper›PMID 26400376›Full record

ArticlePublic health action2015

Impact of intensified case-finding strategies on childhood TB case registration in Nepal.

B Joshi, P Chinnakali, A Shrestha, M Das, A M V Kumar, R Pant, R Lama, R R Sarraf, S P Dumre, A D Harries

Abstract read
In one paragraph

Article in Public health action, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Tuberculosis care models for children and adolescents: a scoping review.Bulletin of the World Health Organization · 2022
    Article
  11. Article
  12. Review
  13. Childhood Tuberculosis: An Under Prioritized Disease in Nepal.JNMA; journal of the Nepal Medical Association · 2021
    Article
  14. The Impact of Funding on Childhood TB Case Detection in Pakistan.Tropical medicine and infectious disease · 2019
    Article
  15. Article
  16. Tuberculosis in Infants and Children.Microbiology spectrum · 2017
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

B JoshiFriends Affected and Infected Together In Hand (FAITH), Kathmandu, Nepal.
P ChinnakaliJawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
A ShresthaNational Tuberculosis Centre, Thimi, Bhaktapur, Nepal.
M DasMédecins Sans Frontières Operational Centre Brussels, New Delhi, India.
A M V KumarInternational Union Against Tuberculosis and Lung Disease (The Union), South-East Asian Regional Office, New Delhi, India.
R PantNational Tuberculosis Centre, Thimi, Bhaktapur, Nepal.
R LamaFriends Affected and Infected Together In Hand (FAITH), Kathmandu, Nepal.
R R SarrafSano Paila ( A little step ), Lalitpur, Nepal.
S P DumreWorld Health Organization Country Office for Nepal, Lalitpur, Nepal.
A D HarriesThe Union, Paris, France ; London School of Hygiene & Tropical Medicine, London, UK.

Funding

World Health Organization 001
6 · The paper itself

Abstract

settingSeven intervention districts with intensified childhood tuberculosis (TB) case-finding strategies implemented by a non-governmental organisation and seven control districts under the National Tuberculosis Programme, Nepal.

objectivesTo assess the differences in childhood TB case registrations and case registration rates per 100 000 population between two time periods (Year 1 = March 2012-March 2013 and Year 2 = March 2013-March 2014) in intervention and control districts.

designRetrospective record review using routinely collected data.

resultsChildhood TB cases increased from 271 to 360 between Years 1 and 2 in the intervention districts (case registration rate from 18.2 to 24.2/100 000) and from 97 to 113 in the control districts (13.4 to 15.6/100 000): the increases were significantly higher in the intervention districts compared with the control districts. The increases were also significantly higher in children aged 0-4 years and in those with smear-negative pulmonary TB and extra-pulmonary TB. Of the various case-finding strategies, household contact screening, private-public mix services and mobile health chest camps produced the highest yield of TB.

conclusionA package of intensified case-finding strategies in children was associated with an increase in childhood TB case registrations in Nepal. Additional diagnostic approaches to increase case registrations also need to be considered.

Indexed as

non-governmental organisationoperational researchpaediatric tuberculosisSORT ITTB REACH

Identifiers

PMID26400376
PMCPMC4487484

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.