Evidence map›Paper›PMID 26400179›Full record

ArticleNucleic acids research2016

hPSCreg--the human pluripotent stem cell registry.

Stefanie Seltmann, Fritz Lekschas, Robert Müller, Harald Stachelscheid, Marie-Sophie Bittner, Weiping Zhang, Luam Kidane, Anna Seriola, Anna Veiga, Glyn Stacey and 1 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  19. Ultrarapid Delayed Rectifier KFrontiers in cell and developmental biology · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stefanie SeltmannBerlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, 13353, Germany.
Fritz LekschasBerlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, 13353, Germany.
Robert MüllerBerlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, 13353, Germany.
Harald StachelscheidBerlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, 13353, Germany Berlin Institute of Health-Stem Cell Core Facility, 13353 Berlin, Germany.
Marie-Sophie BittnerBerlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, 13353, Germany.
Weiping ZhangBerlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, 13353, Germany.
Luam KidaneNational Institute for Biological Standards and Control, South Mimms EN63QG, UK.
Anna SeriolaCenter of Regenerative Medicine in Barcelona, Barcelona Stem Cell Bank, Barcelona 08003, Spain.
Anna VeigaCenter of Regenerative Medicine in Barcelona, Barcelona Stem Cell Bank, Barcelona 08003, Spain.
Glyn StaceyNational Institute for Biological Standards and Control, South Mimms EN63QG, UK.
Andreas KurtzBerlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, 13353, Germany Seoul National University, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul 151-742, Republic of Korea andreas.kurtz@charite.de.

Funding

Medical Research Council MR/L01324X/1
6 · The paper itself

Abstract

The human pluripotent stem cell registry (hPSCreg), accessible at http://hpscreg.eu, is a public registry and data portal for human embryonic and induced pluripotent stem cell lines (hESC and hiPSC). Since their first isolation the number of hESC lines has steadily increased to over 3000 and new iPSC lines are generated in a rapidly growing number of laboratories as a result of their potentially broad applicability in biomedicine and drug testing. Many of these lines are deposited in stem cell banks, which are globally established to store tens of thousands of lines from healthy and diseased donors. The Registry provides comprehensive and standardized biological and legal information as well as tools to search and compare information from multiple hPSC sources and hence addresses a translational research need. To facilitate unambiguous identification over different resources, hPSCreg automatically creates a unique standardized name for each cell line registered. In addition to biological information, hPSCreg stores extensive data about ethical standards regarding cell sourcing and conditions for application and privacy protection. hPSCreg is the first global registry that holds both, manually validated scientific and ethical information on hPSC lines, and provides access by means of a user-friendly, mobile-ready web application.

Indexed as

Cell LineEmbryonic Stem CellsInduced Pluripotent Stem CellsRegistriesHumansInternet

Identifiers

PMID26400179
PMCPMC4702942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.