Evidence map›Paper›PMID 26400039›Full record

ArticleBioinformatics (Oxford, England)2016

PathwaysWeb: a gene pathways API with directional interactions, expanded gene ontology, and versioning.

James M Melott, John N Weinstein, Bradley M Broom

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James M MelottDepartment of Bioinformatics and Computational Biology and.
John N WeinsteinDepartment of Bioinformatics and Computational Biology and Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Bradley M BroomDepartment of Bioinformatics and Computational Biology and.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
UNIVERSITY OF TEXAS MD ANDERSON SPORE IN OVARIAN CANCERP50CA083639 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BAST, ROBERT C · 1999 to 2015
$33.0M
Integrative Pipeline for Analysis & Translational Application of TCGA Data (GDAC)U24CA143883 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI AKBANI, REHAN, MILLS, GORDON B. · 2009 to 2016
$10.6M
Next-Generation Clustered Heat Maps for fluent, interactive exploration of omic data: Cloud Pilot SupplementU24CA199461 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BROOM, BRADLEY MCINTOSH, WEINSTEIN, JOHN N · 2015 to 2019
$2.7M
NCI NIH HHS CA083639NCI NIH HHS CA143883NCI NIH HHS P30 CA016672NCI NIH HHS P50 CA083639NCI NIH HHS U24 CA143883NCI NIH HHS U24 CA199461
6 · The paper itself

Abstract

unlabelledPathwaysWeb is a resource-based, well-documented web system that provides publicly available information on genes, biological pathways, Gene Ontology (GO) terms, gene-gene interaction networks (importantly, with the directionality of interactions) and links to key-related PubMed documents. The PathwaysWeb API simplifies the construction of applications that need to retrieve and interrelate information across multiple, pathway-related data types from a variety of original data sources. PathwaysBrowser is a companion website that enables users to explore the same integrated pathway data. The PathwaysWeb system facilitates reproducible analyses by providing access to all versions of the integrated datasets. Although its GO subsystem includes data for mouse, PathwaysWeb currently focuses on human data. However, pathways for mouse and many other species can be inferred with a high success rate from human pathways. AVAILABILITY AND IMPLEMENTATION: PathwaysWeb can be accessed via the Internet at http://bioinformatics.mdanderson.org/main/PathwaysWeb:Overview. CONTACT: jmmelott@mdanderson.org SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

Databases, FactualGene OntologyGene Regulatory NetworksInternetProtein Interaction MapsSignal TransductionAlgorithmsAnimalsComputational BiologyHumansInformation Storage and RetrievalMice

Identifiers

PMID26400039
PMCPMC4907393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.