Evidence map›Paper›PMID 26399752›Full record

Trial reportScientific reports2015

Noninvasive Ventilation for Preterm Twin Neonates with Respiratory Distress Syndrome: A Randomized Controlled Trial.

Long Chen, Li Wang, Jie Li, Nan Wang, Yuan Shi

Abstract readRandomized Controlled TrialTwin Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
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  17. [Application of real world study in neonatal medicine].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Long ChenDepartment of Pediatrics, Daping Hospital, Research Institute of Surgery, Third Military Medical University, Chongqing, 400042, China.
Li WangDepartment of Pediatrics, Daping Hospital, Research Institute of Surgery, Third Military Medical University, Chongqing, 400042, China.
Jie LiDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400014, China.
Nan WangDepartment of Pediatrics, Daping Hospital, Research Institute of Surgery, Third Military Medical University, Chongqing, 400042, China.
Yuan ShiDepartment of Pediatrics, Daping Hospital, Research Institute of Surgery, Third Military Medical University, Chongqing, 400042, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noninvasive ventilation has been proven to be effective strategies for reducing the need for endotracheal ventilation in preterm infant with respiratory distress syndrome (RDS), however the best option needs to be further determined. A single center, paired design, randomized, controlled trial was conducted between Jan 2011 and July 2014. Preterm twins with RDS were included. One of a pair was randomized to NIPPV, while another to NCPAP. Surfactant was administrated as rescue treatment. The primary outcome was the need for endotracheal ventilation. The secondary outcomes were the complications. 143 pairs were randomized and 129 pairs finished the trial. The rates of endotracheal ventilation did not differ significantly between NIPPV and NCPAP groups (11.9% vs 19.6%, P = 0.080). This difference was not observed in the subgroup of infants who received surfactant therapy (11.1% vs 19.7%, P = 0.087). No secondary outcomes also differed significantly between the two groups. NIPPV did not result in a significantly lower incidence of intubation as compared with NCPAP in preterm twins with RDS.

Indexed as

Infant, PrematureNoninvasive VentilationApgar ScoreFemaleHumansInfant, NewbornMaleRespiratory Distress Syndrome, NewbornTreatment Outcome

Identifiers

PMID26399752
PMCPMC4585863

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.