ReviewJournal of epidemiology2015
Estimation of Cancer Burden Attributable to Infection in Asia.
Review in Journal of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Burden of gastric cancer attributable to Helicobacter pylori in 27 countries from seven geographic regions in 2022.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026Pooled it
- Incidence patterns of rare cancer in southeast Asian and western Pacific countries (RARECAREnet Asia project): a study using population-based cancer registry data, 2011-2015.The Lancet regional health. Southeast Asia · 2025Article
- Evaluating the relationship between familial poverty,Frontiers in public health · 2025Article
- The role of the S100A8/S100A9 in gastric tumor progression.Scientific reports · 2024Article
- The impact of health education interventions on HPV vaccination uptake, awareness, and acceptance among people under 30 years old in India: a literature review with systematic search.Frontiers in reproductive health · 2023Review
- Review
- Burden of cancer attributable to infection in Japan in 2015.GHM open · 2021Article
- Review
- Attributable Causes of Cancer in Vietnam.JCO global oncology · 2020Article
- Article
- Comparison of risk adjustment methods in patients with liver disease using electronic medical record data.BMC gastroenterology · 2017Article
- Article
- Dermatomyositis Induced by Hepatitis B Virus-related Hepatocellular Carcinoma: A Case Report and Review of the Literature.Internal medicine (Tokyo, Japan) · 2017Review
- Detection of human papillomavirus-16 DNA in archived clinical samples of breast and lung cancer patients from North Pakistan.Journal of cancer research and clinical oncology · 2016Article
- Chronic hepatitis infection is associated with extrahepatic cancer development: a nationwide population-based study in Taiwan.BMC cancer · 2016Article
- Development and validation of method for defining conditions using Chinese electronic medical record.BMC medical informatics and decision making · 2016Article
- Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSome infectious agents have been shown to be human carcinogens. The current study focused on estimation of cancer burden attributable to infection in different regions of Asia.
methodsBy systematically reviewing previous studies of the infection prevalence data of 13 countries in Asia and relative risks of specific cancers, we calculated the population attributable fraction of carcinogenic infections. Using data from GLOBOCAN 2012, the overall country-specific and gender-specific number of new cancer cases and deaths resulting from infection were estimated.
resultsAcross 13 principal Asian countries, the average prevalence and range was 6.6% (0.5% in Japanese women to 15.0% in Vietnamese men) for hepatitis B virus (HBV), 2.6% (0.3% in Iran to 5.1% in Saudi Arabia) for hepatitis C virus (HCV), 7.9% (2.8% in Pakistan to 17.7% in China) for human papillomavirus (HPV), and 61.8% (12.8% in Indonesia to 91.7% in Bangladesh) for Helicobacter pylori (HP). The estimated total number of cancer cases and deaths caused by infection in these 13 countries were 1 212 026 (19.6% of all new cancer cases) and 908 549 (22.0% of all deaths from cancer). The fractions of cancer incidence attributable to infection were 19.7% and 19.5% in men and women, respectively. The percentages of cancer deaths attributable to infection were 21.9% and 22.1% in men and women, respectively. Among the main infectious agents, HP was responsible for 31.5% of infection-related cancer cases and 32.8% of infection-related cancer deaths, followed by HBV (28.6% of new cases and 23.8% of deaths), HPV (22.0% of new cases and 27.3% of deaths), and HCV (12.2% of new cases and 10.6% of deaths).
conclusionsApproximately one quarter of all cancer cases and deaths were infection-associated in Asia, which could be effectively prevented if appropriate long-term controls of infectious agents were applied.
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