ArticleJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
Sleep-disordered breathing in patients with cystic fibrosis.
Article in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sleep disorders in cystic fibrosis: A systematic review and meta-analysis.Sleep medicine reviews · 2020Pooled it
- Paranasal Sinus CT and Polysomnographic Findings in Adults with Cystic Fibrosis: Implications for Obstructive Sleep Apnea.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026Article
- Calcitonin Gene-Related Peptide Level in Cystic Fibrosis Patients.Life (Basel, Switzerland) · 2024Article
- Breathing patterns during sleep and their relationship with FEV1 in pediatric patients with cystic fibrosis residing at high altitude.Frontiers in pediatrics · 2024Article
- Sleep-Disordered Breathing and Chronic Respiratory Infections: A Narrative Review in Adult and Pediatric Population.International journal of molecular sciences · 2023Review
- Obstructive sleep apnea and nocturnal hypoxemia in adult patients with cystic fibrosis.BMC pulmonary medicine · 2022Article
- Risk factors for obstructive sleep apnea in cystic fibrosis.Pediatric pulmonology · 2022Article
- Insomnia in adults with cystic fibrosis: strong association with anxiety/depression and impaired quality of life.BMC pulmonary medicine · 2021Article
- Association of sleep disorders with heart rate variability in children and adolescents with cystic fibrosis.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2021Article
- Sleep-disordered breathing in cystic fibrosis.Sleep medicine · 2020Article
- Sleep disturbances and their impact in pediatric cystic fibrosis.Sleep medicine reviews · 2018Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo test the hypothesis that disease severity in patients with cystic fibrosis (CF) is correlated with an increased risk of sleep apnea.
methodsA total of 34 CF patients underwent clinical and functional evaluation, as well as portable polysomnography, spirometry, and determination of IL-1β levels.
resultsMean apnea-hypopnea index (AHI), SpO2 on room air, and Epworth Sleepiness Scale score were 4.8 ± 2.6, 95.9 ± 1.9%, and 7.6 ± 3.8 points, respectively. Of the 34 patients, 19 were well-nourished, 6 were at nutritional risk, and 9 were malnourished. In the multivariate model to predict the AHI, the following variables remained significant: nutritional status (β = -0.386; p = 0.014); SpO2 (β = -0.453; p = 0.005), and the Epworth Sleepiness Scale score (β = 0.429; p = 0.006). The model explained 51% of the variation in the AHI.
conclusionsThe major determinants of sleep apnea were nutritional status, SpO2, and daytime sleepiness. This knowledge not only provides an opportunity to define the clinical risk of having sleep apnea but also creates an avenue for the treatment and prevention of the disease.
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