ArticleJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
Cocaine-induced pulmonary changes: HRCT findings.
Article in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 39 citations in OpenAlex.
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- Pulmonary Complications of Substance Abuse: Pathophysiology, Diagnosis, and Management Strategies.Addiction & health · 2025Review
- Drug-Induced Pulmonary Fibrosis: National Database Analysis.Biomedicines · 2024Article
- Crack lung with toxic cerebral vasculitis: Case report.Radiology case reports · 2024Article
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- An Important Clinical Condition in Differential Diagnosis of Coronavirus Disease 2019: Crack Lung.Thoracic research and practice · 2023Article
- Changes in lung function in adolescents with substance use disorders: an exploratory study.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023Observational
- Chest CT scan for the screening of air anomalies at risk of pulmonary barotrauma for the initial medical assessment of fitness to dive in a military population.Frontiers in physiology · 2022Article
- HRCT Patterns of Drug-Induced Interstitial Lung Diseases: A Review.Diagnostics (Basel, Switzerland) · 2020Review
- Cocaine-Induced Giant Bullous Emphysema.Case reports in medicine · 2020Article
- Methamphetamine use association with pulmonary diseases: a retrospective investigation of hospital discharges in California from 2005 to 2011.ERJ open research · 2019Article
- Pneumomediastinum as a complication of cocaine abuse.Clinical medicine (London, England) · 2019Article
- Risk factors for tuberculosis: diabetes, smoking, alcohol use, and the use of other drugs.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2018Review
- Pulmonary foreign body granulomatosis in a chronic user of powder cocaine.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaArticle
- Cocaine-induced pulmonary complications: A diagnosis of waiting and watching.Lung India : official organ of Indian Chest SocietyArticle
- Pulmonary talcosis caused by intravenous methadone injection.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaArticle
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Authors and funding
11 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate HRCT scans of the chest in 22 patients with cocaine-induced pulmonary disease.
methodsWe included patients between 19 and 52 years of age. The HRCT scans were evaluated by two radiologists independently, discordant results being resolved by consensus. The inclusion criterion was an HRCT scan showing abnormalities that were temporally related to cocaine use, with no other apparent causal factors.
resultsIn 8 patients (36.4%), the clinical and tomographic findings were consistent with "crack lung", those cases being studied separately. The major HRCT findings in that subgroup of patients included ground-glass opacities, in 100% of the cases; consolidations, in 50%; and the halo sign, in 25%. In 12.5% of the cases, smooth septal thickening, paraseptal emphysema, centrilobular nodules, and the tree-in-bud pattern were identified. Among the remaining 14 patients (63.6%), barotrauma was identified in 3 cases, presenting as pneumomediastinum, pneumothorax, and hemopneumothorax, respectively. Talcosis, characterized as perihilar conglomerate masses, architectural distortion, and emphysema, was diagnosed in 3 patients. Other patterns were found less frequently: organizing pneumonia and bullous emphysema, in 2 patients each; and pulmonary infarction, septic embolism, eosinophilic pneumonia, and cardiogenic pulmonary edema, in 1 patient each.
conclusionsPulmonary changes induced by cocaine use are varied and nonspecific. The diagnostic suspicion of cocaine-induced pulmonary disease depends, in most of the cases, on a careful drawing of correlations between clinical and radiological findings.
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