Evidence map›Paper›PMID 26398623›Full record

ReviewPharmacogenetics and genomics2015

PharmGKB summary: succinylcholine pathway, pharmacokinetics/pharmacodynamics.

Maria L Alvarellos, Ellen M McDonagh, Sephalie Patel, Howard L McLeod, Russ B Altman, Teri E Klein

Abstract readReview
In one paragraph

Review in Pharmacogenetics and genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Genetic Testing forPharmacogenomics and personalized medicine · 2020
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Hepatoprotective Effects of Ethyl Acetate Extract ofIranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria L AlvarellosDepartments of aGenetics bBioengineering, Stanford University, Stanford, California cDepartment of Anesthesiology dMoffitt Cancer Center, DeBartolo Family Personalized Medicine Institute, Tampa, Florida, USA eGenomics England, Queen Mary University of London, London, UK.
Ellen M McDonagh
Sephalie Patel
Howard L McLeod
Russ B Altman
Teri E Klein

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
PharmGKB: pharmacogenomics knowledge for precision medicineR24GM061374 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO, KLEIN, TERI ELLEN · 2010 to 2018
$25.2M
A Knowledge Base for Clinically Relevant Genes and VariantsU01HG007437 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BERG, JONATHAN S, EVANS, JAMES PHILIP · 2013 to 2016
$9.0M
Genetic Etiology of Cancer Drug ResponseR01CA161608 · NCI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI WILTSHIRE, TIM, WRIGHT, FRED A. · 2012 to 2021
$4.0M
NCI NIH HHS P30 CA07629NCI NIH HHS P30 CA076292NCI NIH HHS R01 CA161608NHGRI NIH HHS U01 HG007437NIGMS NIH HHS R24 GM061374PHS HHS NIH/NIGMS R24 GM61374
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApneaButyrylcholinesteraseCalcium ChannelsCalcium Channels, L-TypeHumansHyperkalemiaMalignant HyperthermiaMetabolism, Inborn ErrorsNeuromuscular Depolarizing AgentsPharmacogeneticsPolymorphism, Single NucleotideRyanodine Receptor Calcium Release ChannelSuccinylcholineButyrylcholinesteraseCACNA1S protein, humanCalcium ChannelsCalcium Channels, L-TypeNeuromuscular Depolarizing AgentsRyanodine Receptor Calcium Release ChannelSuccinylcholine

Identifiers

PMID26398623
PMCPMC4631707

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.