SynthesisPloS one2015
Influenza-Associated Disease Burden in Kenya: A Systematic Review of Literature.
Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- The burden of seasonal influenza in Italy: A systematic review of influenza-related complications, hospitalizations, and mortality.Influenza and other respiratory viruses · 2022Pooled it
- Routine immunisation coverage in the context of seasonal influenza vaccine introduction for children in Nakuru and Mombasa counties in Kenya, 2019-21: an observational study.The Lancet. Global health · 2025Observational
- Insights from respiratory virus co-infections.World journal of virology · 2024Review
- Estimating Influenza Illnesses Averted by Year-Round and Seasonal Campaign Vaccination for Young Children, Kenya.Emerging infectious diseases · 2024Article
- Article
- Article
- Potential health and economic impact of paediatric vaccination using next-generation influenza vaccines in Kenya: a modelling study.BMC medicine · 2023Article
- [Health Technology Assessment: a value-based tool for the evaluation of healthcare technologies. Reassessment of the cell-culture-derived quadrivalent influenza vaccine: Flucelvax TetraJournal of preventive medicine and hygiene · 2022Article
- Characterization of influenza infection in a high-income urban setting in Nairobi, Kenya.Tropical medicine and health · 2022Article
- Seasonal influenza vaccination in Kenya: an economic evaluation using dynamic transmission modelling.BMC medicine · 2020Article
- Burden and seasonality of medically attended influenza like illness (ILI) in Ethiopia, 2012 to 2017.BMC infectious diseases · 2020Article
- The Epidemiology and Burden of Influenza B/Victoria and B/Yamagata Lineages in Kenya, 2012-2016.Open forum infectious diseases · 2019Article
- The cost of influenza-associated hospitalizations and outpatient visits in Kenya.BMC public health · 2019Article
- Building laboratory capacity to detect and characterize pathogens of public and global health security concern in Kenya.BMC public health · 2019Article
- Vitamin D Deficiency is Associated with Increased Use of Antimicrobials among Preschool Girls in Ethiopia.Nutrients · 2019Article
- Burden and epidemiology of influenza- and respiratory syncytial virus-associated severe acute respiratory illness hospitalization in Madagascar, 2011-2016.Influenza and other respiratory viruses · 2019Article
- Article
- Article
- Epidemiology of influenza in Ethiopia: findings from influenza sentinel surveillance and respiratory infection outbreak investigations, 2009-2015.BMC infectious diseases · 2018Article
- The effects of the attributable fraction and the duration of symptoms on burden estimates of influenza-associated respiratory illnesses in a high HIV prevalence setting, South Africa, 2013-2015.Influenza and other respiratory viruses · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn Kenya data on the burden of influenza disease are needed to inform influenza control policies.
methodsWe conducted a systematic review of published data describing the influenza disease burden in Kenya using surveillance data collected until December 2013. We included studies with laboratory confirmation of influenza, well-defined catchment populations, case definitions used to sample patients for testing and a description of the laboratory methods used for influenza testing. Studies with or without any adjustments on the incidence rates were included.
resultsTen studies reporting the incidence of medically-attended and non-medically attended influenza were reviewed. For all age groups, the influenza positive proportion ranged from 5-10% among hospitalized patients, and 5-27% among all medically-attended patients (a combination of in- and outpatients). The adjusted incidence rate of hospitalizations with influenza among children < 5 years ranged from 2.7-4.7 per 1,000 [5.7 per 1,000 in children < 6 months old], and were 7-10 times higher compared to persons aged ≥ 5 years. The adjusted incidence of all medically-attended influenza among children aged < 5 years ranged from 13.0-58.0 per 1,000 compared to 4.3-26.0 per 1,000 among persons aged ≥ 5 years.
conclusionsOur review shows an expanding set of literature on disease burden associated with influenza in Kenya, with a substantial burden in children under five years of age. Hospitalizations with influenza in these children were 2-3 times higher than reported in the United States. These findings highlight the possible value of an influenza vaccination program in Kenya, with children < 5 years and pregnant women being potentially important targets.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.