ArticleBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2015
Intensity of swimming exercise influences aortic reactivity in rats.
Article in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Article
- High-fat Diet Coupled with Aerobic Exercise Has a Sexually Dimorphic Effect on the Biochemical Profile and Anxiety-like Behaviour of Adolescent Wistar Rats.Annals of neurosciences · 2025Article
- Dose-response association between physical activity and diagnosed hypertension in 2.4 million Korean population: Korea Community Health Survey 2009-2022.Clinical hypertension · 2025Article
- Nandrolone decanoate impairs gastrointestinal motility and duodenal morphometry in moderately exercised rats.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2024Article
- Magnesium ions improve vasomotor function in exhausted rats.PloS one · 2023Article
- Cardiovascular Risk Factors and Physical Activity for the Prevention of Cardiovascular Diseases in the Elderly.International journal of environmental research and public health · 2021Review
- Supplementation withNutrients · 2021Article
- High-intensity exercise in hypoxia improves endothelial function via increased nitric oxide bioavailability in C57BL/6 mice.Acta physiologica (Oxford, England) · 2021Article
- Physical Training Is a Potential Modifier of Risk for Contrast-Induced Acute Kidney Injury in Diabetes Mellitus.BioMed research international · 2020Article
- Exercise-Induced Regulation of Redox Status in Cardiovascular Diseases: The Role of Exercise Training and Detraining.Antioxidants (Basel, Switzerland) · 2019Review
- Exercise for Prevention and Relief of Cardiovascular Disease: Prognoses, Mechanisms, and Approaches.Oxidative medicine and cellular longevity · 2019Review
- Exercise training improves vascular reactivity in ovariectomized rats subjected to myocardial infarction.PloS one · 2019Article
- Acute Aerobic Swimming Exercise Induces Distinct Effects in the Contractile Reactivity of Rat Ileum to KCl and Carbachol.Frontiers in physiology · 2016Article
- Chronic aerobic swimming exercise promotes functional and morphological changes in rat ileum.Bioscience reports · 2015Article
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5 authors.
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Abstract
Exercise is known to cause a vasodilatory response; however, the correlation between the vasorelaxant response and different training intensities has not been investigated. Therefore, this study evaluated the vascular reactivity and lipid peroxidation after different intensities of swimming exercise in rats. Male Wistar rats (aged 8 weeks; 250-300 g) underwent forced swimming for 1 h whilst tied to loads of 3, 4, 5, 6, and 8% of their body weight, respectively (groups G3, G4, G5, G6 and G8, respectively; n=5 each). Immediately after the test, the aorta was removed and suspended in an organ bath. Cumulative relaxation in response to acetylcholine (10-12-10-4 M) and contraction in response to phenylephrine (10-12-10-5 M) were measured. Oxidative stress was estimated by determining malondialdehyde concentration. The percentages of aorta relaxation were significantly higher in G3 (7.9±0.20), G4 (7.8±0.29), and G5 (7.9±0.21), compared to the control group (7.2±0.04), while relaxation in the G6 (7.4±0.25) and G8 (7.0±0.06) groups was similar to the control group. In contrast, the percentage of contraction was significantly higher in G6 (8.8 ±0.1) and G8 (9.7±0.29) compared to the control (7.1±0.1), G3 (7.3±0.2), G4 (7.2±0.1) and G5 (7.2±0.2%) groups. Lipid peroxidation levels in the aorta were similar to control levels in G3, G4 and G5, but higher in G6 and G8, and significantly higher in G8 (one-way ANOVA). These results indicate a reduction in vasorelaxing activity and an increase in contractile activity in rat aortas after high-intensity exercise, followed by an increase in lipid peroxidation.
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