Evidence map›Paper›PMID 26397956›Full record

ArticleJournal of the American Chemical Society2015

Nanostructure of Materials Determined by Relayed Paramagnetic Relaxation Enhancement.

Judith Schlagnitweit, Mingxue Tang, Maria Baias, Sara Richardson, Staffan Schantz, Lyndon Emsley

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Judith SchlagnitweitInstitut de Science Analytiques, Centre de RMN à très hauts champs, Université de Lyon , CNRS/ENS de Lyon/UCB Lyon1, 69100 Villeurbanne, France.
Mingxue TangInstitut de Science Analytiques, Centre de RMN à très hauts champs, Université de Lyon , CNRS/ENS de Lyon/UCB Lyon1, 69100 Villeurbanne, France.
Maria BaiasInstitut de Science Analytiques, Centre de RMN à très hauts champs, Université de Lyon , CNRS/ENS de Lyon/UCB Lyon1, 69100 Villeurbanne, France.
Sara RichardsonR&D Pharmaceutical Development, AstraZeneca , 431 50 Mölndal, Sweden.
Staffan SchantzR&D Pharmaceutical Development, AstraZeneca , 431 50 Mölndal, Sweden.
Lyndon EmsleyInstitut de Science Analytiques, Centre de RMN à très hauts champs, Université de Lyon , CNRS/ENS de Lyon/UCB Lyon1, 69100 Villeurbanne, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Particle and domain sizes strongly influence the properties of materials. Here we present an NMR approach based on paramagnetic relaxation enhancement (PRE) relayed by spin diffusion (SD), which allows us to determine lengths in the nm-μm range. We demonstrate the method on multicomponent organic polymer mixtures by selectively doping one component with a paramagnetic center in order to measure the domain size in a second component. Using this approach we determine domain sizes in ethyl cellulose/hydroxypropyl cellulose film coatings in pharmaceutical controlled release formulations. Here we measure particle sizes ranging from around 50 to 200 nm.

Indexed as

CelluloseMagnetic Resonance SpectroscopyNanostructuresCelluloseethyl cellulosehydroxypropylcellulose

Identifiers

PMID26397956
PMCPMC4598824

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.