Evidence map›Paper›PMID 26396966›Full record

ArticleJournal of biomedical physics & engineering2015

Effect of 900 MHz Electromagnetic Radiation on the Induction of ROS in Human Peripheral Blood Mononuclear Cells.

E Kazemi, S M J Mortazavi, A Ali-Ghanbari, S Sharifzadeh, R Ranjbaran, Z Mostafavi-Pour, F Zal, M Haghani

Open access · greenAbstract read
In one paragraph

Article in Journal of biomedical physics & engineering, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

E KazemiRadiobiology department, School of paramedical sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
S M J MortazaviMedical Physics Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran ; The Center for Research on Protection against Ionizing and Non-ionizing Radiation, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
A Ali-GhanbariTelecommunication Department, School of Engineering, Shiraz University, Shiraz, Iran.
S SharifzadehDiagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
R RanjbaranDiagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Z Mostafavi-PourBiochemistry Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
F ZalBiochemistry Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
M HaghaniThe Center for Research on Protection against Ionizing and Non-ionizing Radiation, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite numerous studies over a decade, it still remains controversial about the biological effects of RF EMF emitted by mobile phone telephony.

objectiveHere we investigated the effect of 900 MHz GSM on the induction of oxidative stress and the level of intracellular reactive oxygen species (ROS) in human mononuclear cells, monocytes and lymphocytes as defence system cells.

method6 ml Peripheral Blood samples were obtained from 13 healthy volunteers (21-30 year-old). Each sample was devided into 2 groups: one was exposed RF radiation emitted from a mobile phone simulator for 2 hour and the other used as control group which was not exposed to any fields. After that, mononuclear cells were isolated from peripheral blood by density gradient centrifugation in Ficoll-Paque. The intracellular ROS content in monocytes and lymphocytes was measured by the CM-H2DCFDA fluorescence probe using flowcytometry technique.

resultsOur results showed significant increase in  ROS production after exposure in population rich in monocytes. This effect was not significant in population rich in lymphocytes in comparison with non exposed cells.

conclusionThe results obtained in this study clearly showed the oxidative stress induction capability of RF electromagnetic field in the portion of PBMCs mostly in monocytes, like the case of exposure to micro organisms, although the advantages or disadvantages of this effect should be evaluated.

Indexed as

Electromagnetic RadiationHuman Peripheral Blood Mononuclear CellsMobile phoneRadiofrequency (RF)Reactive Oxygen Species (ROS)

Identifiers

PMID26396966
PMCPMC4576871
OpenAlexW1533773296

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.