Evidence map›Paper›PMID 26396949›Full record

ArticleIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2014

Allergic Rhinitis in Children: A Randomized Clinical Trial Targeted at Symptoms.

Nicola Mansi, Gabriele D'Agostino, Antonella Silvia Scirè, Giada Morpurgo, Dario Gregori, Achal Gulati, Valerio Damiani

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04957927 (Effectiveness of Montelukast Versus Intranasal Fluticasone Propionate in the Management of Allergic Rhinitis Among Children 02 to 05 Years of Age), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04957927 phase4unknown statusnot on this mapstarted 2020, after this paper: background citation

Effectiveness of Montelukast Versus Intranasal Fluticasone Propionate in the Management of Allergic Rhinitis Among Children 02 to 05 Years of Age

TypeinterventionalSponsorUsama AzharRan2020 to 2021Enrolled60ConditionsAllergic RhinitisArmsEffectiveness of Montelukast Versus Intranasal Fluticasone Propionate in the Management of Allergic Rhinitis Among Children 02 to 05 Years of Age
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Nicola MansiS.C. di Otorinolaringoiatria della A.O.R.N. Santobono Pausilipon di Napoli, Naples, Italy.
Gabriele D'AgostinoS.C. di Otorinolaringoiatria della A.O.R.N. Santobono Pausilipon di Napoli, Naples, Italy.
Antonella Silvia ScirèZeta Research Srl, Trieste, Italy.
Giada MorpurgoZeta Research Srl, Trieste, Italy.
Dario GregoriUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Via Loredan, 18, 35121 Padua, Italy.
Achal GulatiE.N.T. Department, Maulana Azad Medical College and LN, New Delhi, India.
Valerio DamianiENT Department San Giovanni Addolorata Hospital, Rome, Italy.
Azienda Ospedaliera San Giovanni Addolorata · ITMaulana Azad Medical College · INUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergic rhinitis (AR) underlies many symptoms and complications which severely affect children's quality of life. This two-arm study aimed at evaluate the efficacy and safety of the medical device Narivent(®) versus topical corticosteroids in the symptomatic management of allergic rhinitis in paediatric patients. A randomized study was conducted. Forty subjects with a diagnosis of allergic rhinitis were randomized to receive one puff of Narivent(®) into each nostril twice daily for 30 days (n = 20) or to receive one puff of topical intranasal corticosteroid into each nostril twice daily for 30 days (n = 20). In both treatment arms, severity of major symptoms related to AR, including nasal congestion, rhinorrhoea, sneezing and nasal itching, was assessed subjectively on a 0-100 mm visual analogue scale. Nasal congestion, rhinorrhoea and sneezing improved significantly after 30 days of treatment with Narivent(®). Similarly, in topical steroids group severity of all subjective symptoms decreased significantly. Narivent(®) appears to be efficacious in treating nasal congestion and other major symptoms in children with AR over a 30-day period, showing comparable results to intranasal corticosteroids therapy but with a better safety profile.

Indexed as

Allergic rhinitisAnti-inflammatoryAnti-oedematousChildrenIntranasal corticosteroidsOsmotically-acting medical device

Identifiers

PMID26396949
PMCPMC4571470
OpenAlexW2038785717

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.