Evidence map›Paper›PMID 26396502›Full record

ReviewPatient preference and adherence2015

Interventional tools to improve medication adherence: review of literature.

Elísio Costa, Anna Giardini, Magda Savin, Enrica Menditto, Elaine Lehane, Olga Laosa, Sergio Pecorelli, Alessandro Monaco, Alessandra Marengoni

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Patient preference and adherence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Coaching Through Technology: A Systematic Review into Efficacy and Effectiveness for the Ageing Population.International journal of environmental research and public health · 2020
    Pooled it
  3. Pooled it
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  5. Interventions to improve adherence to lipid-lowering medication.The Cochrane database of systematic reviews · 2016
    Pooled it
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74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elísio CostaUCIBIO, REQUIMTE, Faculty of Pharmacy, University of Porto, Porto, Portugal.
Anna GiardiniPsychology Unit, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Montescano (PV), Pavia, Italy.
Magda SavinEuropean Association of Pharmaceutical Full-line Wholesalers, Brussels, Belgium.
Enrica MendittoCIRFF/Center of Pharmacoeconomics, School of Pharmacy, University of Naples FedericoII, Nápoles, Italy.
Elaine LehaneCatherine McAuley School of Nursing and Midwifery, Brookfield Health Sciences Complex, University College Cork, Cork, Ireland.
Olga LaosaCentro de Investigación Clínica del Anciano Fundación para la Investigación Biomédica, Hospital Universitario de Getafe, Madrid, Spain.
Sergio PecorelliItalian Medicines Agency - AIFA, Rome, Italy ; University of Brescia, Brescia, Italy.
Alessandro MonacoItalian Medicines Agency - AIFA, Rome, Italy.
Alessandra MarengoniDepartment of Clinical and Experimental Science, University of Brescia, Brescia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medication adherence and persistence is recognized as a worldwide public health problem, particularly important in the management of chronic diseases. Nonadherence to medical plans affects every level of the population, but particularly older adults due to the high number of coexisting diseases they are affected by and the consequent polypharmacy. Chronic disease management requires a continuous psychological adaptation and behavioral reorganization. In literature, many interventions to improve medication adherence have been described for different clinical conditions, however, most interventions seem to fail in their aims. Moreover, most interventions associated with adherence improvements are not associated with improvements in other outcomes. Indeed, in the last decades, the degree of nonadherence remained unchanged. In this work, we review the most frequent interventions employed to increase the degree of medication adherence, the measured outcomes, and the improvements achieved, as well as the main limitations of the available studies on adherence, with a particular focus on older persons.

Indexed as

chronic diseasescognitive impairmentcomplianceelderlynonadherencetools

Identifiers

PMID26396502
PMCPMC4576894

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.