Evidence map›Paper›PMID 26396181›Full record

ArticleAge and ageing2015

Pain and falls and fractures in community-dwelling older men.

Troels Munch, Stephanie L Harrison, Elizabeth Barrett-Connor, Nancy E Lane, Michael C Nevitt, John T Schousboe, Marcia Stefanick, Peggy M Cawthon

Open access · bronzeAbstract read
In one paragraph

Article in Age and ageing, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
10.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. The Osteoporotic Fractures in Men study (MrOS): a 25-yr landmark study of skeletal health in older men.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Multi-Dimensional Impact of Chronic Low Back Pain among Underserved African American and Latino Older Adults.International journal of environmental research and public health · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. The silent epidemic of chronic pain in older adults.Progress in neuro-psychopharmacology & biological psychiatry · 2019
    Review
  16. Joint pain and falls among women with breast cancer on aromatase inhibitors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Article
  17. Article
  18. Parkinson's Disease and Symptomatic Osteoarthritis Are Independent Risk Factors of Falls in the Elderly.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

Troels MunchDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus 8200, Denmark California Pacific Medical Center Research Institute, San Francisco, CA, USA.
Stephanie L HarrisonCalifornia Pacific Medical Center Research Institute, San Francisco, CA, USA.
Elizabeth Barrett-ConnorUniversity of California, San Diego, CA, USA.
Nancy E LaneInternal Medicine, University of California, Davis, Davis, CA, USA.
Michael C NevittUniversity of California San Francisco, San Francisco, CA, USA.
John T SchousboePark Nicollet Institute for Research and Education, St Louis Park, MN, USA.
Marcia StefanickDepartment of Medicine, Stanford University, Stanford Prevention Research Center, Palo Alto, CA, USA.
Peggy M CawthonCalifornia Pacific Medical Center Research Institute, San Francisco, CA, USA.
California Pacific Medical Center · USAarhus University Hospital · DKPark Nicollet Foundation · USStanford University · USUniversity of California, Davis · USUniversity of California, San Diego · USUniversity of California, San Francisco · US

Funding

OREGON CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024140 · NCRR · OREGON HEALTH & SCIENCE UNIVERSITY · PI ORWOLL, ERIC S. · 2006 to 2011
$61.1M
OSTEOPOROTIC FRACTURES IN MENU01AG018197 · NIA · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI CUMMINGS, STEVEN RON · 1999 to 2011
$12.7M
Osteoporotic Fractures in Men (MrOS) - San Francisco Coordinating CenterU01AR066160 · NIAMS · CALIFORNIA PACIFIC MED CTR RES INSTITUTE · PI CUMMINGS, STEVEN RON · 2013 to 2017
$9.3M
Osteoporotic Fractures in Men: MrOS Renewal-PortlandU01AR045647 · NIAMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ORWOLL, ERIC S. · 1999 to 2011
$6.7M
Translation of Quantitative Imaging in OsteoarthritisP50AR060752 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SOUZA, RICHARD BRIAN · 2011 to 2015
$6.2M
Sex Differences in response to an exercise for hyperkyphosisP50AR063043 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KATZMAN, WENDY BETH · 2012 to 2017
$5.7M
Osteporotic Fractures in Men (MrOS)- Admin CenterU01AG027810 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI ORWOLL, ERIC S. · 2006 to 2017
$5.1M
Osteoporotic Fractures in Men - Renewal: PittsburghU01AR045654 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CAULEY, JANE ANN · 1999 to 2011
$5.1M
OSTEOPOROTIC FRACTURES IN MENU01AR045614 · NIAMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ENSRUD, KRISTINE · 1999 to 2011
$4.0M
Osteoporotic Fractures in MenU01AR045583 · NIAMS · STANFORD UNIVERSITY · PI STEFANICK, MARCIA L. · 1999 to 2011
$4.0M
Osteoporotic Fractures in Men - MrOS RenewalU01AR045580 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BARRETT-CONNOR, ELIZABETH L · 1999 to 2011
$3.9M
Osteoporotic Fractures in Men- MrOS Renewal - BirminghamU01AR045632 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SHIKANY, JAMES M · 1999 to 2011
$3.6M
NCRR NIH HHS UL1 RR024140NIAMS NIH HHS AR052000NIAMS NIH HHS K24-AR048841NIAMS NIH HHS P50AR060752NIAMS NIH HHS P50 AR063043NIAMS NIH HHS U01 AR066160NIAMS NIH HHS U01 AR45580NIAMS NIH HHS U01 AR45583NIAMS NIH HHS U01 AR45614NIAMS NIH HHS U01 AR45632NIAMS NIH HHS U01 AR45647NIAMS NIH HHS U01 AR45654NIA NIH HHS U01-AG027810NIA NIH HHS U01 AG042143NIA NIH HHS U01 AG18197
6 · The paper itself

Abstract

backgroundPain may reduce stability and increase falls and subsequent fractures in older men.

objectivesTo examine the association between joint pain and any pain with falls, hip and non-spine fractures in older community-dwelling men.

designA cohort study. SETTING AND

participantsAnalyses included 5,993 community-dwelling men aged ≥65 years from the MrOS cohort. MEASUREMENTS: Pain at hip, knee and elsewhere (any) was assessed by self-report. Men reported falls via questionnaires mailed 3× per year during the year following the baseline visit. Fractures were verified centrally. Mean follow-up time for fractures was 9.7 (SD 3.1) years. Logistic regression models estimated likelihood of falls and proportional hazards models estimated risk of fractures. Models were adjusted for age, BMI, race, smoking, alcohol use, medications use, co-morbidities and arthritis; fracture models additionally adjusted for bone mineral density.

resultsOne quarter (25%, n = 1,519) reported ≥1 fall; 710 reported ≥2 falls in the year after baseline. In multivariate models, baseline pain at hip, knee or any pain increased likelihood of ≥1 fall and ≥2 falls over the following year. For example, knee pain increased likelihood of ≥1 fall (odds ratio, OR 1.44; 95% confidence interval, CI 1.25-1.65) and ≥2 falls (OR 1.75; 95% CI 1.46-2.10). During follow-up, 936 (15.6%) men suffered a non-spine fracture (n = 217, 3.6% hip). In multivariate models, baseline pain was not associated with incident hip or non-spine fractures.

conclusionsAny pain, knee pain and hip pain were each strong independent risk factors for falls in older men. Increased risk of falls did not translate into an increased risk of fractures.

Indexed as

Accidental FallsAgedArthralgiaBone DensityCohort StudiesFractures, BoneHumansIndependent LivingLogistic ModelsMaleRisk FactorsSurveys and QuestionnairescohortfallfractureMrOSolder peoplepain

Identifiers

PMID26396181
PMCPMC4621231
OpenAlexW2174328972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.