SynthesisCurrent urology reports2015
Systematic Review of Urologic Outcomes from Tethered Cord Release in Occult Spinal Dysraphism in Children.
Synthesis in Current urology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Evidence-based position paper of the UEMS PRM on the role of Physical and Rehabilitation Medicine (PRM) physician in the management of children and adults with spinal dysraphism.European journal of physical and rehabilitation medicine · 2022Pooled it
- A systematic review of the quality of conduct and reporting of systematic reviews and meta-analyses in paediatric surgery.PloS one · 2017Pooled it
- Symptomatic and Urodynamic Outcomes After Spinal Cord De-Tethering in Primary Tethered Cord Patients.Neurourology and urodynamics · 2026Article
- Pre- and postoperative urodynamic risk stratification in infants and young children undergoing tethered cord release.Journal of pediatric urology · 2026Article
- The expression of GSTP1 in the filum terminale of children with tethered cord syndrome.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Association between orthopedic manifestations and tethered cord release in patients with spina bifida: a survival analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Treatment of an anterior cervicothoracic myelomeningocele together with spine deformity correction in a child: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- Filum terminale transection in pediatric tethered cord syndrome: a single center, population-based, cohort study of 95 cases.Acta neurochirurgica · 2022Article
- A systematic review and meta-analysis of minimally invasive surgery in children with occult tethered cord syndrome.Translational pediatrics · 2022Article
- Importance of Physical Examination and Imaging in the Detection of Tethered Cord Syndrome.Global pediatric health · 2019Article
- Urodynamic outcomes of detethering in children: experience with 46 pediatric patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tethered cord syndrome describes a condition of multisystem end organ dysfunction due to fixation of the spinal cord. This systematic review focuses on the closed skin variant of this condition, occult spinal dysraphism. The embryology, pathophysiology, presentation, and classification of occult spinal dysraphism are explained to develop a simple framework for discussions regarding this often confusing condition. Following Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines, we synthesized urologic outcome data after tethered cord release in children from 17 studies performed over the past 25 years. These results prompted several conclusions. First, the different subgroups and different nomenclature of tethered cord syndrome are often confused, making interpretation of results difficult. Second, untethering has a positive effect on urologic symptoms and urodynamics parameters. Third, timing of untethering is important: early intervention prevents significant long-term traction aiming to avoid irreversible neurologic damage. Fourth, pediatric urologists and neurosurgeons have an important role in diagnosing and treating this condition and should work closely as part of a multidisciplinary team.
Indexed as
Identifiers
26396132What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.