Evidence map›Paper›PMID 26395578›Full record

Trial reportTrials2015

Ghana randomized air pollution and health study (GRAPHS): study protocol for a randomized controlled trial.

Darby W Jack, Kwaku Poku Asante, Blair J Wylie, Steve N Chillrud, Robin M Whyatt, Kenneth A Ae-Ngibise, Ashlinn K Quinn, Abena Konadu Yawson, Ellen Abrafi Boamah, Oscar Agyei and 4 more

3 registry-linked trialsAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 64 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01335490 nacompletednot on this map

Intervening to Improve Birth Weight and Infant Respiratory Health in Rural Ghana

TypeinterventionalSponsorColumbia UniversityRan2013 to 2016Enrolled1,414ConditionsVery Low Birth Weight Baby, PneumoniaArmsCook stoves, either Biolite wood stove, or liquified petroleum gas stove plus fuel
NCT03352830 nacompletednot on this mapstarted 2017, after this paper: background citation

Understanding Adoption of Clean Cookstoves

TypeinterventionalSponsorColumbia UniversityRan2017 to 2018Enrolled781ConditionsBehavior, Consumer, Health Knowledge, Attitudes, Practice, Health AttitudeArmsRANAS Behavior Change Intervention, Infrastructural Intervention - Direct Delivery
NCT03498755 nacompletednot on this mapstarted 2018, after this paper: background citation

The Invisible Fishers: Empowering and Safeguarding Women in Fisheries Value Chains in Ghana to Reduce Anemia

TypeinterventionalSponsorUniversity of MichiganRan2018 to 2019Enrolled120ConditionsAnemiaArmsMobile phone audio messaging, Peer-to-peer learning, Conditional cash transfer, Entrepreneurship training, Market price information
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Darby W JackMailman School of Public Health, Columbia University, New York, NY, USA. dj2183@cumc.columbia.edu.
Kwaku Poku AsanteKintampo Health Research Centre, Ghana Health Service, Brong Ahafo Region, Kintampo, Ghana. kwakupoku.asante@kintampo-hrc.org.
Blair J WylieDivision of Maternal-Fetal Medicine, Vincent Department of Obstetrics and Gynecology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. BWYLIE@partners.org.
Steve N ChillrudLamont-Doherty Earth Observatory of Columbia University, New York, NY, USA. chilli@ldeo.columbia.edu.
Robin M WhyattMailman School of Public Health, Columbia University, New York, NY, USA. rmw5@cumc.columbia.edu.
Kenneth A Ae-NgibiseKintampo Health Research Centre, Ghana Health Service, Brong Ahafo Region, Kintampo, Ghana. kenneth.asayah@kintampo-hrc.org.
Ashlinn K QuinnMailman School of Public Health, Columbia University, New York, NY, USA. akq3@cumc.columbia.edu.
Abena Konadu YawsonKintampo Health Research Centre, Ghana Health Service, Brong Ahafo Region, Kintampo, Ghana. abena.yawson@kintampo-hrc.org.
Ellen Abrafi BoamahKintampo Health Research Centre, Ghana Health Service, Brong Ahafo Region, Kintampo, Ghana. ellen.boamah@kintampo-hrc.org.
Oscar AgyeiKintampo Health Research Centre, Ghana Health Service, Brong Ahafo Region, Kintampo, Ghana. oscar.agyei@kintampo-hrc.org.
Mohammed MujtabaKintampo Health Research Centre, Ghana Health Service, Brong Ahafo Region, Kintampo, Ghana. mohammed.mujtaba@kintampo-hrc.org.
Seyram KaaliKintampo Health Research Centre, Ghana Health Service, Brong Ahafo Region, Kintampo, Ghana. kaali.seyram@kintampo.hrc.org.
Patrick KinneyMailman School of Public Health, Columbia University, New York, NY, USA. plk3@cumc.columbia.edu.
Seth Owusu-AgyeiKintampo Health Research Centre, Ghana Health Service, Brong Ahafo Region, Kintampo, Ghana. seth.owusu-agyei@kintampo-hrc.org.

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Intervening to Improve Birth Weight and Infant Respiratory Health in Rural GhanaR01ES019547 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KINNEY, PATRICK LOTT · 2011 to 2016
$4.5M
Interdisciplinary Training in Climate and HealthT32ES023770 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHAMAN, JEFFREY L · 2014 to 2019
$1.5M
Household air pollution in Tanzania, placental health and pregnancy outcomeK23ES021471 · NIEHS · MASSACHUSETTS GENERAL HOSPITAL · PI WYLIE, BLAIR JOHNSON · 2012 to 2016
$1.3M
NIEHS NIH HHS 1R01ES019547NIEHS NIH HHS ES009089NIEHS NIH HHS K23 ES021471NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R01 ES019547NIEHS NIH HHS T32 ES023770
6 · The paper itself

Abstract

backgroundHousehold air pollution exposure is a major health risk, but validated interventions remain elusive. METHODS/

designThe Ghana Randomized Air Pollution and Health Study (GRAPHS) is a cluster-randomized trial that evaluates the efficacy of clean fuels (liquefied petroleum gas, or LPG) and efficient biomass cookstoves in the Brong-Ahafo region of central Ghana. We recruit pregnant women into LPG, efficient cookstove, and control arms and track birth weight and physician-assessed severe pneumonia incidence in the first year of life. A woman is eligible to participate if she is in the first or second trimester of pregnancy and carrying a live singleton fetus, if she is the primary cook, and if she does not smoke. We hypothesize that babies born to intervention mothers will weigh more and will have fewer cases of physician-assessed severe pneumonia in the first year of life. Additionally, an extensive personal air pollution exposure monitoring effort opens the way for exposure-response analyses, which we will present alongside intention-to-treat analyses. Major funding was provided by the National Institute of Environmental Health Sciences, The Thrasher Research Fund, and the Global Alliance for Clean Cookstoves. DISCUSSION: Household air pollution exposure is a major health risk that requires well-tested interventions. GRAPHS will provide important new evidence on the efficacy of both efficient biomass cookstoves and LPG, and will thus help inform health and energy policies in developing countries.

trial registrationThe trial was registered with clinicaltrials.gov on 13 April 2011 with the identifier NCT01335490 .

Indexed as

BiomassHousingAir Pollution, IndoorBirth WeightCookingEquipment DesignFemaleGasesGhanaHumansIncidenceInfantInfant, NewbornInhalation ExposurePetroleumPneumoniaGasesPetroleum

Identifiers

PMID26395578
PMCPMC4579662

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.