Evidence map›Paper›PMID 26395477›Full record

ArticleDevelopment (Cambridge, England)2015

Large-scale live imaging of adult neural stem cells in their endogenous niche.

Nicolas Dray, Sébastien Bedu, Nelly Vuillemin, Alessandro Alunni, Marion Coolen, Monika Krecsmarik, Willy Supatto, Emmanuel Beaurepaire, Laure Bally-Cuif

Abstract read
In one paragraph

Article in Development (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Neural stem cell heterogeneity in adult hippocampus.Cell regeneration (London, England) · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Apical size andScience advances · 2023
    Article
  11. A pan-metazoan concept for adult stem cells: the wobbling Penrose landscape.Biological reviews of the Cambridge Philosophical Society · 2022
    Article
  12. Review
  13. Quantifiable Intravital Light Sheet Microscopy.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nicolas DrayParis-Saclay Institute for Neuroscience, CNRS UMR9197 - Université Paris-Sud, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Building 5, Gif-sur-Yvette F-91198, France.
Sébastien BeduParis-Saclay Institute for Neuroscience, CNRS UMR9197 - Université Paris-Sud, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Building 5, Gif-sur-Yvette F-91198, France.
Nelly VuilleminLaboratory for Optics and Biosciences, École Polytechnique, Centre National de la Recherche Scientifique (UMR 7645) and Institut National de la Santé et de la Recherche Médicale (U1182), Palaiseau 91128, France.
Alessandro AlunniParis-Saclay Institute for Neuroscience, CNRS UMR9197 - Université Paris-Sud, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Building 5, Gif-sur-Yvette F-91198, France.
Marion CoolenParis-Saclay Institute for Neuroscience, CNRS UMR9197 - Université Paris-Sud, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Building 5, Gif-sur-Yvette F-91198, France.
Monika KrecsmarikParis-Saclay Institute for Neuroscience, CNRS UMR9197 - Université Paris-Sud, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Building 5, Gif-sur-Yvette F-91198, France.
Willy SupattoLaboratory for Optics and Biosciences, École Polytechnique, Centre National de la Recherche Scientifique (UMR 7645) and Institut National de la Santé et de la Recherche Médicale (U1182), Palaiseau 91128, France.
Emmanuel BeaurepaireLaboratory for Optics and Biosciences, École Polytechnique, Centre National de la Recherche Scientifique (UMR 7645) and Institut National de la Santé et de la Recherche Médicale (U1182), Palaiseau 91128, France emmanuel.beaurepaire@polytechnique.edu bally-cuif@inaf.cnrs-gif.fr.
Laure Bally-CuifParis-Saclay Institute for Neuroscience, CNRS UMR9197 - Université Paris-Sud, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Building 5, Gif-sur-Yvette F-91198, France emmanuel.beaurepaire@polytechnique.edu bally-cuif@inaf.cnrs-gif.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Live imaging of adult neural stem cells (aNSCs) in vivo is a technical challenge in the vertebrate brain. Here, we achieve long-term imaging of the adult zebrafish telencephalic neurogenic niche and track a population of >1000 aNSCs over weeks, by taking advantage of fish transparency at near-infrared wavelengths and of intrinsic multiphoton landmarks. This methodology enables us to describe the frequency, distribution and modes of aNSCs divisions across the entire germinal zone of the adult pallium, and to highlight regional differences in these parameters.

Indexed as

Stem Cell NicheAnimalsAnimals, Genetically ModifiedBrainCell LineageCell ProliferationGreen Fluorescent ProteinsHydrogen-Ion ConcentrationImage Processing, Computer-AssistedLuminescent ProteinsMicroscopy, FluorescenceNeural Stem CellsNeuroimagingRed Fluorescent ProteinTelencephalonTemperatureGreen Fluorescent ProteinsLuminescent ProteinsRed Fluorescent ProteinLive imagingMultiphoton microscopyNeural stem cellPalliumSHG/THGZebrafish

Identifiers

PMID26395477
PMCPMC4631764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.