Evidence map›Paper›PMID 26395352›Full record

Trial reportClinical oral investigations2016

Silver diamine fluoride and glass ionomer differentially remineralize early caries lesions, in situ.

Ratichanok Nantanee, Busayarat Santiwong, Chutima Trairatvorakul, Hidenori Hamba, Junji Tagami

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Effect of silver diamine fluoride on adhesion and microleakage of a pit and fissure sealant to tooth enamel: in vitro trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2018
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ratichanok NantaneeDepartment of Pediatric Dentistry, Faculty of Dentistry, Chulalongkorn University, 34 Henry Dunant Road, Pathumwan, Bangkok, 10330, Thailand.
Busayarat SantiwongDepartment of Pediatric Dentistry, Faculty of Dentistry, Chulalongkorn University, 34 Henry Dunant Road, Pathumwan, Bangkok, 10330, Thailand.
Chutima TrairatvorakulDepartment of Pediatric Dentistry, Faculty of Dentistry, Chulalongkorn University, 34 Henry Dunant Road, Pathumwan, Bangkok, 10330, Thailand. ctrairat@gmail.com.
Hidenori HambaDepartment of Cariology and Operative Dentistry, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.
Junji TagamiDepartment of Cariology and Operative Dentistry, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.
Chulalongkorn University · THTokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of the present study was to evaluate the percent mean mineral density (MD) change of early caries lesions after the application of silver diamine fluoride (SDF) or glass ionomer cement (GIC). MATERIALS AND

methodsThis double-blind, crossover study involved two experimental phases of 28 days each. Thirty-two pairs of enamel slabs were created from the proximal surfaces of 16 premolars. Each pair of artificial carious slabs was randomly divided into the control or test group (38 % SDF or GIC). The slabs were attached to orthodontic brackets and bonded to the maxillary first permanent molars of 16 subjects for 28 days. After a 7-day washout period between phases, the subjects received the other material for the second phase. The mean MD of the lesions was measured by microcomputed tomography.

resultsSDF yielded a percent mean MD increase at a depth of 0-84 μm, although increase in the GIC group was observed at a depth of 24-108 μm. The percent mean MD changes of the SDF and GIC groups were similar (p = 0.100) and significantly higher than in control (p < 0.001, p = 0.003, respectively).

conclusionsThe two materials increased the percent mean MD change of early proximal caries lesions to a similar extent, but with different spatial patterns. CLINICAL RELEVANCE: Due to deeper level of GIC remineralization, the refractive index of the GIC applied enamel might be closer to sound enamel. Hence, GIC is recommended for remineralization of anterior teeth. SDF staining makes it unsuitable for use in anterior teeth; thus, it is reserved for use in posterior teeth.

Indexed as

BicuspidCariostatic AgentsCross-Over StudiesDental CariesDental EnamelDouble-Blind MethodFemaleFluorides, TopicalGlass Ionomer CementsHumansMaleMolarQuaternary Ammonium CompoundsSilver CompoundsThailandTooth RemineralizationCariostatic AgentsFluorides, TopicalGlass Ionomer CementsQuaternary Ammonium CompoundsSilver Compoundssilver diamine fluorideCaries lesionsGlass ionomer cementMineral densitySilver diamine fluoride

Identifiers

PMID26395352
OpenAlexW1697695722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.