Evidence map›Paper›PMID 26395273›Full record

ArticleEating and weight disorders : EWD2016

Epicardial adipose tissue and signs of metabolic syndrome in children.

Giuseppe Barbaro, Alessandra Piedimonte, Maria Podagrosi, Roberta Mercurio, Antonella Mosca, Miriam D'Avanzo, Andrea Vania

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Article in Eating and weight disorders : EWD, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giuseppe BarbaroDepartment of Experimental Medicine, Medical Pathophysiology, Rome "Sapienza" University, Rome, Italy.
Alessandra PiedimonteCentre for Paediatric Dietetics and Nutrition, Department of Paediatrics and Paediatric Neuropsychiatry, Rome "Sapienza" University, Viale Regina Elena 324, Rome, Italy.
Maria PodagrosiCentre for Paediatric Dietetics and Nutrition, Department of Paediatrics and Paediatric Neuropsychiatry, Rome "Sapienza" University, Viale Regina Elena 324, Rome, Italy.
Roberta MercurioCentre for Paediatric Dietetics and Nutrition, Department of Paediatrics and Paediatric Neuropsychiatry, Rome "Sapienza" University, Viale Regina Elena 324, Rome, Italy.
Antonella MoscaCentre for Paediatric Dietetics and Nutrition, Department of Paediatrics and Paediatric Neuropsychiatry, Rome "Sapienza" University, Viale Regina Elena 324, Rome, Italy.
Miriam D'AvanzoDepartment of Radiology, Rome "Sapienza" University, Rome, Italy.
Andrea VaniaCentre for Paediatric Dietetics and Nutrition, Department of Paediatrics and Paediatric Neuropsychiatry, Rome "Sapienza" University, Viale Regina Elena 324, Rome, Italy. andrea.vania@uniroma1.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to investigate the possible correlation between epicardial adipose tissue (EAT) thickness and predictive parameters for metabolic syndrome (MS) in overweight/obese prepubertal children.

methods73 prepubertal children, average age of 8.22 years, with no endocrine or syndromic causes of obesity or under drug therapy for chronic disease were enrolled. Weight, height, body circumferences and skinfolds' thickness were measured. BMI, BMI z score (z-BMI) and waist-to-height ratio (WtHR) were calculated. Standard MS-related laboratory parameters were assessed. Finally, all children underwent echocardiographic measurement of EAT.

resultsA positive correlation between EAT and z-BMI was found only among overweight/obese children (r = 0.43, p = 0.001). In particular, data showed that 89 % of our sample had a waist (W) >90th percentile. Statistical differences in diastolic blood pressure (DBP; p < 0.01) and EAT (p = 0.02) were observed on comparing W <90th percentile vs W >90th percentile patients. Besides, in patients with W >90th percentile and family history of risk factors for MS, the value of EAT correlated positively with z-BMI, W, WtHR, triglycerides (Tg), insulin and homeostatic model assessment of insulin resistance and negatively with HDL.

conclusionsThe EAT and the markers of MS probably share the same pathogenetic factors. Further studies might elucidate whether EAT deserves to be included among the diagnostic factors of MS.

Indexed as

Adipose TissueBody WeightChildEchocardiographyFemaleHumansInsulin ResistanceMaleMetabolic SyndromeObesityOverweightRisk FactorsWaist CircumferenceChildrenEpicardial adipose tissue thicknessMetabolic syndromeObesity

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.