ArticleBritish journal of cancer2015
Clinical nomogram to predict bone-only metastasis in patients with early breast carcinoma.
Article in British journal of cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed, 40 citations in OpenAlex.
- External validation of a nomogram for de novo bone metastasis in breast cancer: a single-center Mexican cohort.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- A preoperative nomogram incorporating semantic MRI features for predicting breast cancer recurrence: a propensity score-matched cohort study.Frontiers in oncology · 2026Article
- Prognostic factors analysis and nomogram construction of breast cancer patients lung metastases and bone metastases.Surgery open science · 2025Article
- Incidence and Prevalence of Bone Metastases in Different Solid Tumors Determined by Natural Language Processing of CT Reports.Cancers · 2025Article
- A nomogram for individualized prediction for cervical lymph node metastasis of papillary thyroid carcinoma.Gland surgery · 2024Article
- Development and validation of an artificial intelligence model for predicting de novo distant bone metastasis in breast cancer: a dual-center study.BMC women's health · 2024Article
- AI models predicting breast cancer distant metastasis using LightGBM with clinical blood markers and ultrasound maximum diameter.Scientific reports · 2024Article
- Development and validation of AI models using LR and LightGBM for predicting distant metastasis in breast cancer: a dual-center study.Frontiers in oncology · 2024Article
- Implications for surveillance for breast cancer patients based on the internally and externally validated BRENDA-metastatic recurrence score.Breast cancer research and treatment · 2023Article
- MR imaging phenotypes and features associated with pathogenic mutation to predict recurrence or metastasis in breast cancer.BMC cancer · 2023Article
- Invasive Lobular Carcinoma Has Worse Outcome Compared with Invasive Ductal Carcinoma in Stage IV Breast Cancer with Bone-Only Metastasis.Breast care (Basel, Switzerland) · 2022Article
- Nomogram Models Based on the Gene Expression in Prediction of Breast Cancer Bone Metastasis.Journal of healthcare engineering · 2022Article
- Prognosis of metastasis based on age and serum analytes after follow-up of non-metastatic lung cancer patients.Translational oncology · 2021Article
- Development of KAM score to predict metastasis and worse survival in breast cancer.American journal of cancer research · 2021Article
- Nomogram for predicting the risk of bone metastasis in breast cancer: a SEER population-based study.Translational cancer research · 2020Article
- Nomogram for Estimating Overall Survival in Patients With Metastatic Pancreatic Cancer.Pancreas · 2020Article
- Novel prognostic nomograms for female patients with breast cancer and bone metastasis at presentation.Annals of translational medicine · 2020Article
- Construction of a MicroRNA-Based Nomogram for Prediction of Lung Metastasis in Breast Cancer Patients.Frontiers in genetics · 2020Article
- Development and validation of a novel nomogram for predicting distant metastasis-free survival among breast cancer patients.Annals of translational medicine · 2019Article
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Authors and funding
11 authors at 8 institutions in 2 countries.
Funding
Abstract
backgroundBone is one of the most common sites of distant metastasis in breast cancer. The purpose of this study was to combine selected clinical and pathologic variables to develop a nomogram that can predict the likelihood of bone-only metastasis (BOM) as the first site of recurrence in patients with early breast cancer.
methodsMedical records of patients with non-metastatic breast cancer were retrospectively collected. On the basis of the analysis of patient and tumour characteristics using the Cox proportional hazards regression model, a nomogram to predict BOM was constructed for a 4175-patient-training cohort. The nomogram was validated in an independent cohort of 579 patients.
resultsAmong 4175 patients with non-metastatic breast cancer, 314 developed subsequent BOM. Age, T classification, lymph node status, lymphovascular space invasion, and hormone receptor status were significantly and independently associated with subsequent BOM. The nomogram had a concordance index of 0.69 in the training set and 0.73 in the validation set.
conclusionsWe have developed a clinical nomogram to predict subsequent BOM in patients with non-metastatic breast cancer. Selection of a patient population at high risk for BOM could facilitate research of more specific staging approaches or the selective use of bone-targeted therapy.
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