ArticleInternational journal of molecular sciences2015
Identification and Characterization of CYP9A40 from the Tobacco Cutworm Moth (Spodoptera litura), a Cytochrome P450 Gene Induced by Plant Allelochemicals and Insecticides.
Article in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 64 citations in OpenAlex.
- Functional Annotation and Comparative Analysis of Cytochrome P450 Protein Family Genes in Nine Chironomidae Species.Biology · 2025Article
- Secondary metabolites in host pears defense against two fruit borers and cytochrome-P450-mediated counter-defense.iScience · 2024Article
- Insights into insecticide-resistance mechanisms in invasive species: Challenges and control strategies.Frontiers in physiology · 2022Review
- Resistance in the GenusInsects · 2021Review
- Comparative analyses of transcriptional responses of Dectes texanus LeConte (Coleoptera: Cerambycidae) larvae fed on three different host plants and artificial diet.Scientific reports · 2021Article
- Short term transcriptional responses of P450s to phytochemicals in insects and mites.Current opinion in insect science · 2021Review
- Article
- Insecticidal Terpenes From the Essential Oils ofFrontiers in plant science · 2021Article
- Expression and functional analysis of P450 gene induced tolerance/resistance to lambda-cyhalothrin in quercetin fed larvae of beet armywormSaudi journal of biological sciences · 2020Article
- Insecticidal Activity ofFrontiers in genetics · 2020Article
- RNAi-Mediated Knockdown of Chitin Synthase 1 (Insects · 2019Article
- Tobacco Cutworm (International journal of molecular sciences · 2019Article
- Knock-Down of Gossypol-Inducing Cytochrome P450 Genes Reduced Deltamethrin Sensitivity inInternational journal of molecular sciences · 2019Article
- Article
- Identification and Functional Analysis of a Novel Cytochrome P450 Gene CYP9A105 Associated with Pyrethroid Detoxification in Spodoptera exigua Hübner.International journal of molecular sciences · 2018Article
- De novo transcriptomic analysis of the alimentary tract of the tephritid gall fly, Procecidochares utilis.PloS one · 2018Article
- Volatile β-Ocimene Can Regulate Developmental Performance of Peach AphidFrontiers in plant science · 2018Article
- Identification of Two Cytochrome Monooxygenase P450 Genes, CYP321A7 and CYP321A9, from the Tobacco Cutworm Moth (Spodoptera Litura) and Their Expression in Response to Plant Allelochemicals.International journal of molecular sciences · 2017Article
- RNA-seq of Rice Yellow Stem BorerG3 (Bethesda, Md.) · 2017Article
- Functional Study of Cytochrome P450 Enzymes from the Brown Planthopper (Frontiers in physiology · 2017Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cytochrome P450 monooxygenases (P450s) of insects play crucial roles in the metabolism of endogenous and dietary compounds. Tobacco cutworm moth (Spodoptera litura), an important agricultural pest, causes severe yield losses in many crops. In this study, we identified CYP9A40, a novel P450 gene of S. litura, and investigated its expression profile and potential role in detoxification of plant allelochemicals and insecticides. The cDNA contains an open reading frame encoding 529 amino acid residues. CYP9A40 transcripts were found to be accumulated during various development stages of S. litura and were highest in fifth and sixth instar larvae. CYP9A40 was mainly expressed in the midgut and fat body. Larval consumption of xenobiotics, namely plant allelochemicals (quercetin and cinnamic acid) and insecticides (deltamethrin and methoxyfenozide) induced accumulation of CYP9A40 transcripts in the midgut and fat body. Injection of dsCYP9A40 (silencing of CYP9A40 by RNA interference) significantly increased the susceptibility of S. litura larvae to the tested plant allelochemicals and insecticides. These results indicate that CYP9A40 expression in S. litura is related to consumption of xenobiotics and suggest that CYP9A40 is involved in detoxification of these compounds.
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