Evidence map›Paper›PMID 26393130›Full record

ArticleJournal of clinical and diagnostic research : JCDR2015

Significance of Diagnosing Parasitic Infestation in Evaluation of Unexplained Eosinophilia.

Vinay Khanna, Kriti Tilak, Chiranjay Mukhopadhyay, Ruchee Khanna

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06265870 (Comparison of Outcome Between Specific Anthelminthic Treatment According to Test Results and Empirical Anthelminthic Treatment in Eosinophilic Patient), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06265870 narecruitingnot on this mapstarted 2024, after this paper: background citation

Comparison of Outcome Between Specific Anthelminthic Treatment According to Test Results and Empirical Anthelminthic Treatment in Eosinophilic Patient

TypeinterventionalSponsorPrince of Songkla UniversityRan2024 to 2025Enrolled700ConditionsEosinophiliaArmsAlbendazole, Ivermectin or albendazole
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Vinay KhannaAssociate Professor, Department of Microbiology, Kasturba Medical College, Manipal University , Manipal, Karnataka, India .
Kriti TilakPost Graduate Student, Department of Microbiology, Kasturba Medical College, Manipal University , Manipal, Karnataka, India .
Chiranjay MukhopadhyayProfessor, Department of Microbiology, Kasturba Medical College, Manipal University , Manipal, Karnataka, India .
Ruchee KhannaAssistant Professor, Department of Pathology, Kasturba Medical College, Manipal University , Manipal, Karnataka, India .
Kasturba Medical College, Manipal · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe evaluation of unexplained eosinophilia in an asymptomatic individual has always been a diagnostic challenge and requires understanding about a wide range of probable causative agents. Helminthic infestation and schistosomiasis are the main parasitic causes of eosinophilia. Therefore, the availability of simple and accurate diagnostic tests for detection of parasitic infections can prove to be valuable in early diagnosis and solving the mystery of unexplained eosinophilia. MATERIALS AND

methodsIn the present study we attempt to find an association between relative eosinophilia and parasitic infections and also to find the parasites responsible for eosinophilia in a substantial number of cases. A retrospective study for the presence of eosinophilia was done on 621 cases positive for parasitic infestation.

resultsAmong a total of 621 cases of parasitic infestation only 66 (10.6%) cases were found to have relative eosinophilia. The parasites found to be responsible for eosinophilia were Trichuris trichiura, Ascaris lumbricoides, Strongyloides stercoralis, filarial worm and hook worm.

conclusionFrom the study it is concluded that eosinophilia is not a universal finding in cases with parasitic infestation. Although presence of eosinophilia can serve as one of the many diagnostic clues to look for the presence of helminthic infestation if other non-infectious causes of eosinophilia are ruled out.

Indexed as

Ascaris lumbricoidesHelminthsKarnatakaStrongyloides stercoralisTrichuris trichiura

Identifiers

PMID26393130
PMCPMC4572961
OpenAlexW2234940898

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.