Evidence map›Paper›PMID 26393099›Full record

ArticlePublic health action2014

Treatment outcomes among drug-susceptible tuberculosis patients in Latvia, 2006-2010.

I Lucenko, V Riekstina, J Perevoscikovs, D Mozgis, M Khogali, J Gadoev, P de Colombani, A M V Kumar

Abstract read
In one paragraph

Article in Public health action, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. The impact of smoking on tuberculosis treatment outcomes: a meta-analysis.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

I LucenkoCentre for Disease Prevention and Control of Latvia, Riga, Latvia.
V RiekstinaRiga East Clinical University Hospital, Centre of Tuberculosis and Lung Diseases, Riga, Latvia.
J PerevoscikovsCentre for Disease Prevention and Control of Latvia, Riga, Latvia.
D MozgisCentre for Disease Prevention and Control of Latvia, Riga, Latvia ; Riga Stradins University, Riga, Latvia.
M KhogaliMedical Department, Operational Research Unit, Médecins Sans Frontières (MSF), Operational Centre Brussels, MSF-Luxembourg, Luxembourg.
J GadoevWorld Health Organization (WHO) Country Office, Tashkent, Uzbekistan.
P de ColombaniWHO Regional Office for Europe, Copenhagen, Denmark.
A M V KumarInternational Union Against Tuberculosis and Lung Disease, South-East Asia Regional Office, New Delhi, India.

Funding

World Health Organization 001
6 · The paper itself

Abstract

settingLatvia, an Eastern European country with a high burden of tuberculosis (TB).

objectiveTo describe treatment outcomes among new drug-susceptible TB patients and assess the association of treatment outcomes with selected social determinants and risk factors.

designA retrospective cohort study of patients aged ⩾15 years registered during 2006-2010, with a review of records in the National Tuberculosis Registry.

resultsOf 2476 patients, 1704 (69%) were male; the median age was 42 years. About two thirds of patients were unemployed or retired, 7% were human immunodeficiency virus (HIV) positive and 35% had a history of alcohol use. Treatment success was achieved in 2167 (88%) patients. Older age, unemployment, HIV infection and alcohol use were found to be independently associated with unsuccessful treatment (death, loss to follow-up, failure, transfer out and other). For many variables, including HIV infection, diabetes mellitus and tobacco use, it was not possible to distinguish between 'not recorded' and 'not present' in the registry.

conclusionThe treatment success rate among new drug-susceptible TB patients exceeded the 85% global target for TB control. Additional attention and support is required for most vulnerable patients, such as those who are unemployed or retired, HIV infected and alcohol users. The National TB Registry should be revised to improve definitions and staff should be trained for proper data collection and recording.

Indexed as

risk factorssocial determinantsSORT ITunsuccessful treatment

Identifiers

PMID26393099
PMCPMC4547516

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.