ArticlePublic health action2014
Risk factors associated with loss to follow-up among multidrug-resistant tuberculosis patients in Georgia.
Article in Public health action, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comorbidities and treatment outcomes in multidrug resistant tuberculosis: a systematic review and meta-analysis.Scientific reports · 2018Pooled it
- Risk factors for treatment failure of drug-resistant pulmonary tuberculosis: results from a two-decade data analysis.Journal of thoracic disease · 2026Article
- Pre-treatment loss to follow-up and associated factors among drug-resistant tuberculosis patients diagnosed in Wakiso district, central Uganda.BMC infectious diseases · 2025Article
- Loss to follow-up among adults with drug-resistant TB in Papua New Guinea.Public health action · 2024Article
- Article
- Low BMI increases all-cause mortality rates in patients with drug-resistant TB.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022Article
- Determinant factors for loss to follow-up in drug-resistant tuberculosis patients: the importance of psycho-social and economic aspects.BMC pulmonary medicine · 2021Observational
- Does optimized adherence support improve treatment outcomes in RR / MDR-TB patients on 18-20 months regimen in Tbilisi, Georgia?Journal of infection in developing countries · 2021Article
- Long-Term Mortality and Active Tuberculosis Disease Among Patients Who Were Lost to Follow-Up During Second-Line Tuberculosis Treatment in 2011-2014: Population-Based Study in the Country of Georgia.Open forum infectious diseases · 2021Article
- Factors associated with loss to follow-up among people with tuberculosis in the country of Georgia: a cohort study.Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace · 2021Article
- Article
- Between Curing and Torturing: Burden of Adverse Reaction in Drug-Resistant Tuberculosis Therapy.Patient preference and adherence · 2021Review
- Adverse treatment outcomes in multidrug resistant tuberculosis go beyond the microbe-drug interaction: Results of a multiple correspondence analysis.Biomedica : revista del Instituto Nacional de Salud · 2020Article
- Incidence and predictors of lost to follow-up among drug-resistant tuberculosis patients at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia: a retrospective follow-up study.BMC infectious diseases · 2019Article
- Predictors of Treatment Outcomes among Multidrug Resistant Tuberculosis Patients in Tanzania.Tuberculosis research and treatment · 2019Article
- Predictors of tuberculosis treatment outcomes among a retrospective cohort in rural, Central India.Journal of clinical tuberculosis and other mycobacterial diseases · 2018Article
- Risk factors associated with loss to follow-up from tuberculosis treatment in Tajikistan: a case-control study.BMC infectious diseases · 2017Article
- Factors Associated with Loss to Follow-up during Treatment for Multidrug-Resistant Tuberculosis, the Philippines, 2012-2014.Emerging infectious diseases · 2016Article
- The scourge of tuberculosis and anti-tuberculosis drug resistance in Eastern Europe.Public health action · 2014Article
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Authors and funding
7 authors.
Funding
Abstract
settingGeorgia, a country with a high-burden of multi-drug-resistant tuberculosis (MDR-TB).
objectiveTo determine the proportion of loss to follow-up (LFU) among MDR-TB patients treated nationwide from 2009 to 2011, and associated risk factors.
designRetrospective cohort study involving a review of the National Tuberculosis Programme electronic surveillance database. A Cox proportional hazards model was used to assess risk factors for time to LFU.
resultsAmong 1593 patients, 458 (29%) were lost to follow-up. A total of 1240 MDR-TB patients were included in the final analysis (845 treatment success, 395 LFU). Over 40% of LFU occurred during the first 8 months of MDR-TB treatment; 40% of patients had not achieved culture conversion at the time of LFU. In multivariate analysis, the factors associated with LFU included male sex, illicit drug use, tobacco use, history of previous anti-tuberculosis treatment, site of TB disease, and place and year of initiating treatment.
conclusionLFU was high among MDR-TB patients in Georgia and posed a significant public health risk, as many were culture-positive at the time of LFU. A multi-pronged approach is needed to address the various patient- and treatment-related characteristics associated with LFU.
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