Evidence map›Paper›PMID 26393058›Full record

ArticlePublic health action2013

Market size and sales pattern of tuberculosis drugs in the Philippines.

T Islam, C van Weezenbeek, R Vianzon, A M C G Garfin, T Hiatt, W J Lew, K Tisocki

Open access · diamondAbstract read
In one paragraph

Article in Public health action, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Western Pacific Regional Green Light Committee: progress and way forward.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

T IslamStop TB Unit, World Health Organization, Western Pacific Regional Office, Manila, The Philippines.
C van WeezenbeekKNCV Tuberculosis Foundation, The Hague, The Netherlands.
R VianzonNational Center for Disease Prevention and Control, Department of Health, Manila, The Philippines.
A M C G GarfinNational Center for Disease Prevention and Control, Department of Health, Manila, The Philippines.
T HiattStop TB Unit, World Health Organization, Western Pacific Regional Office, Manila, The Philippines.
W J LewWorld Health Organization, WHO Representative Office Philippines, Manila, The Philippines.
K TisockiEssential Medicines and Health Technologies Unit, World Health Organization, Western Pacific Regional Office, Manila, The Philippines.
World Health Organization Regional Office for the Western Pacific · PHDepartment of Health · PHTuBerculosis Vaccine Initiative · NLWorld Health Organization - Philippines · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo identify the availability, types and quantity of anti-tuberculosis drugs in the public and private sectors from 2007 to 2011 in the Philippines.

methodsAnalysis of the procurement of and sales data on anti-tuberculosis drugs from both the public and private sectors from 2007 to 2011.

resultsPublicly procured anti-tuberculosis drugs were sufficient to treat all reported new tuberculosis (TB) cases from 2007 to 2011 in the Philippines. Nevertheless, the volume of anti-tuberculosis drugs in the private sector would have sufficed for the intensive phase of treatment for an additional 250 000 TB patients annually, assuming compliance with national treatment guidelines. Fixed-dose combination drugs comprised the main bulk (81%) of private market sales, while sales of loose drugs decreased over the years. Combining public and private sales in 2011, 484 725 new TB patients, i.e., 2.4 times the number of notified cases, could have been placed on treatment and treated for at least the intensive phase. Key second-line drugs are not available in the private market, making it impossible to design an adequate treatment regimen for multidrug-resistant TB (MDR-TB) in the private sector.

conclusionAn enormous quantity of anti-tuberculosis drugs was channelled through the private market outside the purview of the Philippine National Tuberculosis Control Program, suggesting significant out-of-pocket expenditure, severe underreporting of TB cases and/or misuse of drugs due to overdiagnosis and overtreatment.

Indexed as

fixed-dose combinationmultidrug-resistant tuberculosisprivate sectorpublic-private mix

Identifiers

PMID26393058
PMCPMC4463147
OpenAlexW2332043886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.