ArticlePublic health action2012
A nested case-control study on relapse predictors among tuberculosis patients treated in Yemen's NTCP.
Article in Public health action, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Pooled it
- Recurrence Rate of Pulmonary Tuberculosis in Patients Treated with the Standard 6-Month Regimen: Findings and Implications from a Prospective Observational Multicenter Study.Tropical medicine and infectious disease · 2023Article
- Knowledge, Attitudes and Practices of the General Population in Yemen Regarding COVID-19: A Cross-Sectional Study.Diseases (Basel, Switzerland) · 2023Article
- Undernutrition is feeding the tuberculosis pandemic: A perspective.Journal of clinical tuberculosis and other mycobacterial diseases · 2022Review
- Risk factors associated with tuberculosis recurrence in South Korea determined using a nationwide cohort study.PloS one · 2022Article
- Tuberculosis recurrences and predictive factors in a vulnerable population in Catalonia.PloS one · 2020Article
- Diabetes-related tuberculosis in the Middle East: an urgent need for regional research.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2015Review
- The incidence of recurrence of tuberculosis and its related factors in smear-positive pulmonary tuberculosis patients in Iran: A retrospective cohort study.Lung India : official organ of Indian Chest SocietyArticle
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
settingThe National Tuberculosis (TB) Control Programme in Yemen.
objectiveTo identify risk factors associated with TB relapse.
methodsIn a prospective nested case-control study, relapse cases were recruited from a cohort of pulmonary TB patients registered between July 2007 and June 2008. Four controls per case were randomly selected from the list of non-relapse patients. Three forms were used for data collection, which included interviews with the participants and review of their medical cards and TB registers. Multivariate logistic regression analysis was performed to identify independent risk factors for relapse.
resultsA relapse rate of 5.7% was found. Multivariate logistic regression analysis showed that unemployment, smoking, presence of cavitations, weight gain, weight loss, non-adherence during the continuation phase and diabetes were significantly associated with relapse (P < 0.05).
conclusionRelapse rates can be reduced by ensuring that patients take their treatment regularly and are counselled effectively to stop smoking. Reinforcing the implementation of the DOTS strategy and strengthening the anti-smoking campaigns are important actions. Action to help unemployed patients, including free services and the creation of new job opportunities, should be adopted. Using rifampicin-based regimens in the treatment of cavitary TB and bi-directional screening in TB and diabetes patients are recommended.
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