Evidence map›Paper›PMID 26392954›Full record

ArticlePublic health action2012

Decentralised care for the management of child contacts of multidrug-resistant tuberculosis.

J A Seddon, A C Hesseling, R Dunbar, H Cox, J Hughes, K Fielding, P Godfrey-Faussett, H S Schaaf

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Article in Public health action, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

J A SeddonDesmond Tutu TB Centre, Faculty of Health Sciences, Stellenbosch University, Tygerberg, South Africa ; Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
A C HesselingDesmond Tutu TB Centre, Faculty of Health Sciences, Stellenbosch University, Tygerberg, South Africa.
R DunbarDesmond Tutu TB Centre, Faculty of Health Sciences, Stellenbosch University, Tygerberg, South Africa.
H CoxMédecins Sans Frontières, Cape Town, South Africa.
J HughesMédecins Sans Frontières, Cape Town, South Africa.
K FieldingDepartment of Infectious Diseases Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
P Godfrey-FaussettDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
H S SchaafDesmond Tutu TB Centre, Faculty of Health Sciences, Stellenbosch University, Tygerberg, South Africa ; Tygerberg Children's Hospital, Tygerberg, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

settingCape Town, South Africa.

objectiveTo determine the number of multidrug-resistant tuberculosis (MDR-TB) child contacts routinely identified by health services, and whether a model of decentralised care improves access.

methodsAll MDR-TB source cases registered in Cape Town from April 2010 to March 2011 were included. All child contacts assessed at hospital and outreach clinics were recorded from May 2010 to June 2011. Electronic probabilistic matching was used to match source cases with potential child contacts; the number of children accessing decentralised (Khayelitsha) and hospital-based care was compared.

resultsOf 1221 MDR-TB source cases identified, 189 (15.5%) were registered in Khayelitsha; 31 (16.4%) had at least one child contact assessed. In contrast, 95 (9.2%) of the 1032 source cases diagnosed in the other Cape Town subdistricts (hospital-based care) had at least one child contact assessed (P = 0.003). Children in Khayelitsha were seen at a median of 71 days (interquartile range [IQR] 37-121 days) after source case diagnosis compared to 90 days (IQR 56-132 days) in other subdistricts (P = 0.15).

conclusionAlthough decentralised care led to an increased number of child contacts being evaluated, both models led to the assessment of a small number of potential child MDR-TB contacts, with considerable delay in assessment.

Indexed as

accesscarechilddecentraliseddrug-resistantpaediatrictuberculosis

Identifiers

PMID26392954
PMCPMC4463039

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.