Molecular profiling of MPS1 gene silencing in U251 glioma cell line.

Uma Shankavaram, Uday Bhanu Maachani, Shuping Zhao, Kevin Camphausen, Anita Tandle

Open access · goldAbstract read

In one paragraph

Article in Genomics data, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact, top 99% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

Mps1 is associated with the BRAFOncology letters · 2019
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Uma ShankavaramRadiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

Uday Bhanu MaachaniRadiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

Shuping ZhaoRadiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

Kevin CamphausenRadiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

Anita TandleRadiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

National Institutes of Health · USNational Cancer Institute · US

Funding

Intramural NIH HHS Z99 CA999999

6 · The paper itself

Abstract

Aneuploidy has been recognized as a common characteristic of cancers. Aneuploidy frequently results from errors of the mitotic checkpoint, the major cell cycle control mechanism that acts to prevent chromosome missegregation. Mutation of the genes that control chromosome segregation during mitosis may explain the high rate of chromosomal instability and aneuploidy, a characteristic of most solid tumors, including glioblastomas (GBM)[1, 2]. Monopolar spindle 1 (

Identifiers

PMID26392922

DOI10.1016/j.gdata.2015.08.003

PMCPMC4573457

OpenAlexW1061398641

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.