Evidence map›Paper›PMID 26392706›Full record

ReviewPharmacognosy reviews

"Ziziphus jujuba": A red fruit with promising anticancer activities.

Zoya Tahergorabi, Mohammad Reza Abedini, Moodi Mitra, Mohammad Hassanpour Fard, Hossein Beydokhti

Abstract readReview
In one paragraph

Review in Pharmacognosy reviews. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Principles and Therapeutics ofJournal of pharmacy & bioallied sciences · 2024
    Review
  7. Article
  8. Plants (Basel, Switzerland) · 2024
    Article
  9. Inhibition of Autophagy AggravatesInternational journal of molecular sciences · 2024
    Article
  10. Article
  11. Article
  12. Effects ofIranian journal of pharmaceutical research : IJPR · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Genus Ziziphus for the treatment of chronic inflammatory diseases.Saudi journal of biological sciences · 2021
    Review
  17. Article
  18. Molecules (Basel, Switzerland) · 2021
    Article
  19. Article
  20. Research advances in bioactive components and health benefits of jujube (Journal of Zhejiang University. Science. B · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zoya TahergorabiDepartment of Pharmacology and Physiology, Berberis and Jujube Research Center, South Khorasan, Birjand, Iran.
Mohammad Reza AbediniDepartment of Pharmacology and Physiology, Berberis and Jujube Research Center, South Khorasan, Birjand, Iran.
Moodi MitraSocial Determinants of Health Research Center, South Khorasan, Birjand, Iran.
Mohammad Hassanpour FardDepartment of Pharmacology and Physiology, Berberis and Jujube Research Center, South Khorasan, Birjand, Iran.
Hossein BeydokhtiDepartments of Public Health, Medical Library and Information Sciences, Birjand University of Medical Sciences, South Khorasan, Birjand, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ziziphus jujuba Mill. (Z. jujuba) is a traditional herb with a long history of use for nutrition and the treatment of a broad spectrum of diseases. It grows mostly in South and East Asia, as well as in Australia and Europe. Mounting evidence shows the health benefits of Z. jujuba, including anticancer, anti-inflammation, antiobesity, antioxidant, and hepato- and gastrointestinal protective properties, which are due to its bioactive compounds. Chemotherapy, such as with cis-diamminedichloroplatinium (CDDP, cisplatin) and its derivatives, is widely used in cancer treatment. It is an effective treatment for human cancers, including ovarian cancer; however, drug resistance is a major obstacle to successful treatment. A better understanding of the mechanisms and strategies for overcoming chemoresistance can greatly improve therapeutic outcomes for patients. In this review article, the bioactive compounds present in Z. jujuba are explained. The high prevalence of many different cancers worldwide has recently attracted the attention of many researchers. This is why our research group focused on studying the anticancer activity of Z. jujuba as well as its impact on chemoresistance both in vivo and in vitro. We hope that these studies can lead to a promising future for cancer patients.

Indexed as

Anticancer activitybioactive compoundschemoresistanceZiziphus jujuba Mill

Identifiers

PMID26392706
PMCPMC4557242

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.