ReviewJournal of endocrinological investigation2016
Etiopathology, clinical features, and treatment of diffuse and multinodular nontoxic goiters.
Review in Journal of endocrinological investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.
- Quality of Life in Patients with Benign Non-Toxic Goiter After Surgical Intervention: A Systematic Review and Meta-Analysis.World journal of surgery · 2022Pooled it
- The compensatory enlargement of the remaining thyroid lobe following hemithyroidectomy is small and without impact on symptom relief.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Trial
- Bleomycin TACE for symptomatic giant nodular goiter.European radiology · 2026Article
- Follicular-Patterned Lesions of the Thyroid Gland.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2026Review
- Thyroid Obstacle During Anterior Cervical Discectomy and Fusion: When to Call Your ENT Surgeon Fellow? A Scoping Review of Individual Patient Data.Asian journal of neurosurgery · 2026Review
- Thyroid disorders in idiopathic inflammatory myopathies: prevalence and related clinical scenarios.BMC endocrine disorders · 2026Article
- Natural product-based interventions for thyroid disorders: mechanisms and applications.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- A Comprehensive Review of Selenium as a Key Regulator in Thyroid Health.Biological trace element research · 2025Review
- Polycystic Ovary Syndrome Attenuates TSH-Lowering Effect of Metformin in Young Women with Subclinical Hypothyroidism.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Impact of Thyroid Arterial Embolization on Clinical and Biochemical Outcomes and Quality of Life in Patients with Nodular and Multinodular Goiter.Cardiovascular and interventional radiology · 2025Article
- Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.Frontiers in microbiology · 2025Article
- The ability of virtual noncontrast images to remove intrinsic and external iodine from the thyroid via dual-layer spectral detector computed tomography.Quantitative imaging in medicine and surgery · 2024Article
- The common pathogenesis of nodular goiter in both sexes: An exploration into gene expression and signaling pathways.Heliyon · 2024Article
- Article
- Clinical features and Surgical Outcomes of Thyroid Goitre Presenting to Ear, Nose and Throat Department of Queen Elizabeth Central Hospital, Blantyre, Malawi.Malawi medical journal : the journal of Medical Association of Malawi · 2024Article
- Surgical Management and Predictors of Postoperative Complications of Retrosternal Goiters: A Retrospective Study.Cureus · 2024Article
- Prevalence of DICER1 variants in large multinodular goiter: thyroid function, clinical and imaging characteristics.Archives of endocrinology and metabolism · 2024Article
- Differences in surgical outcomes between cervical goiter and retrosternal goiter: an international, multicentric evaluation.Frontiers in surgery · 2024Article
- Heterotopic bone formation with extramedullary haematopoiesis in a thyroid nodule.BMJ case reports · 2023Article
- Amyloid goiter secondary to familial Mediterranean fever with E148Q mutation: A unique case.Chronic diseases and translational medicine · 2023Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Goiter, an enlargement of the thyroid gland, is a common problem in clinical practice associated with iodine deficiency, increase in serum thyroid-stimulating hormone (TSH) level, natural goitrogens, smoking, and lack of selenium and iron. Evidence suggests that heredity also has an important role in the etiology of goiter. The current classification divides goiter into diffuse and nodular, which may be further subdivided into toxic (associated with symptoms of hyperthyroidism, suppressed TSH or both), or nontoxic (associated with a normal TSH level). Nodular thyroid disease with the presence of single or multiple nodules requires evaluation due to the risk of malignancy, toxicity, and local compressive symptoms. Measurement of TSH, accurate imaging with high-resolution ultrasonography or computed tomography, and fine-needle aspiration biopsy are the appropriate methods for evaluation and management of goiter. This review discusses the clinical presentation, diagnostic evaluation, and treatment considerations of nontoxic diffuse and nodular goiters.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.