Evidence map›Paper›PMID 26392231›Full record

ArticleDrug and alcohol dependence2015

Substance use and mental diagnoses among adults with and without type 2 diabetes: Results from electronic health records data.

Li-Tzy Wu, Udi E Ghitza, Bryan C Batch, Michael J Pencina, Leoncio Flavio Rojas, Benjamin A Goldstein, Tony Schibler, Ashley A Dunham, Shelley Rusincovitch, Kathleen T Brady

Registry-linked trialAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01966432 (Screening, Brief Intervention, and Referral to Treatment in Primary Care), which is not on this map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01966432 nacompletednot on this map

Screening, Brief Intervention, and Referral to Treatment in Primary Care (SBIRT-PC): An add-on Project to "Duke University Southeastern Diabetes Initiative"

TypeinterventionalSponsorDuke UniversityRan2013 to 2016Enrolled134ConditionsDiabetes Mellitus, Type 2, Substance-related DisordersArmsReferral to Treatment, Brief Intervention
3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Li-Tzy WuDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA; Duke Clinical Research Institute, Duke University, Durham, NC, USA. Electronic address: litzy.wu@duke.edu.
Udi E GhitzaNational Institute on Drug Abuse, Bethesda, MD, USA.
Bryan C BatchDivision of Endocrinology, Duke University Medical Center, Durham, NC, USA.
Michael J PencinaDuke Clinical Research Institute, Duke University, Durham, NC, USA; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.
Leoncio Flavio RojasDuke Clinical Research Institute, Duke University, Durham, NC, USA.
Benjamin A GoldsteinDuke Clinical Research Institute, Duke University, Durham, NC, USA; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.
Tony SchiblerDuke Clinical Research Institute, Duke University, Durham, NC, USA.
Ashley A DunhamDuke Translational Research Institute, Duke University, Durham, NC, USA.
Shelley RusincovitchDuke Translational Research Institute, Duke University, Durham, NC, USA.
Kathleen T BradySouth Carolina Clinical and Translational Research Institute, Medical University of South Carolina, Charleston, SC, USA.

Funding

Southern Consortium Node of the Clinical Trials NetworkU10DA013727 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2000 to 2015
$34.4M
Project-003UG1DA040317 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2015 to 2019
$9.0M
Substance Abuse & Treatment Gaps in Asians, Pacific Islanders & Multiple-race IndR01MD007658 · NIMHD · DUKE UNIVERSITY · PI WU, LI-TZY · 2013 to 2017
$1.8M
Understanding and predicting cardiac events in HD using real-time EHRsK25DK097279 · NIDDK · STANFORD UNIVERSITY · PI GOLDSTEIN, BENJAMIN ALAN · 2013 to 2017
$797k
NIDA NIH HHS U10 DA013727NIDA NIH HHS U10DA013727NIDA NIH HHS UG1 DA040317NIDA NIH HHS UG1DA040317NIDDK NIH HHS K25 DK097279NIMHD NIH HHS R01 MD007658NIMHD NIH HHS R01MD007658
6 · The paper itself

Abstract

backgroundComorbid diabetes and substance use diagnoses (SUD) represent a hazardous combination, both in terms of healthcare cost and morbidity. To date, there is limited information about the association of SUD and related mental disorders with type 2 diabetes mellitus (T2DM).

methodsWe examined the associations between T2DM and multiple psychiatric diagnosis categories, with a focus on SUD and related psychiatric comorbidities among adults with T2DM. We analyzed electronic health record (EHR) data on 170,853 unique adults aged ≥18 years from the EHR warehouse of a large academic healthcare system. Logistic regression analyses were conducted to estimate the strength of an association for comorbidities.

resultsOverall, 9% of adults (n=16,243) had T2DM. Blacks, Hispanics, Asians, and Native Americans had greater odds of having T2DM than whites. All 10 psychiatric diagnosis categories were more prevalent among adults with T2DM than among those without T2DM. Prevalent diagnoses among adults with T2MD were mood (21.22%), SUD (17.02%: tobacco 13.25%, alcohol 4.00%, drugs 4.22%), and anxiety diagnoses (13.98%). Among adults with T2DM, SUD was positively associated with mood, anxiety, personality, somatic, and schizophrenia diagnoses.

conclusionsWe examined a large diverse sample of individuals and found clinical evidence of SUD and psychiatric comorbidities among adults with T2DM. These results highlight the need to identify feasible collaborative care models for adults with T2DM and SUD related psychiatric comorbidities, particularly in primary care settings, that will improve behavioral health and reduce health risk.

Indexed as

AdolescentAdultAgedAged, 80 and overAge FactorsAnxiety DisordersDiabetes Mellitus, Type 2Diagnosis, Dual (Psychiatry)Electronic Health RecordsEthnicityFemaleHumansInternational Classification of DiseasesMaleMental DisordersMiddle AgedAnxiety disorderComorbidityDiabetes mellitusElectronic health recordsMood disorderSubstance use disorder

Identifiers

PMID26392231
PMCPMC4633379

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.