Evidence map›Paper›PMID 26392157›Full record

ArticleThe American journal of tropical medicine and hygiene2015

High Prevalence of Hepatitis B Virus Infection in Young Adults in Ternate, Eastern Indonesia.

Susan Irawati Ie, Turyadi, Erick Sidarta, Arkasha Sadhewa, Gludhug Ariyo Purnomo, Yuyun S M Soedarmono, Mochtar Zein Pattiiha, Meta Dewi Thedja, Alida R Harahap, David H Muljono

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Pathogenic viruses: Molecular detection and characterization.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2020
    Review
  6. Social Determinants of Stigma and Discrimination in Vietnamese Patients with Chronic Hepatitis B.International journal of environmental research and public health · 2019
    Article
  7. Review
  8. Epidemiology of Hepatitis B and C in Republic of Indonesia.Euroasian journal of hepato-gastroenterology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Susan Irawati IeEijkman Institute for Molecular Biology, Jakarta, Indonesia; School of Life Sciences and Technology, Bandung Institute of Technology, Bandung, Indonesia; Central Blood Center, Indonesian Red Cross, Jakarta, Indonesia; Department of Internal Medicine, Ternate General Hospital, Ternate, Maluku, Indonesia; Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Sydney Medical School, University of Sydney, New South Wales, Australia.
TuryadiEijkman Institute for Molecular Biology, Jakarta, Indonesia; School of Life Sciences and Technology, Bandung Institute of Technology, Bandung, Indonesia; Central Blood Center, Indonesian Red Cross, Jakarta, Indonesia; Department of Internal Medicine, Ternate General Hospital, Ternate, Maluku, Indonesia; Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Sydney Medical School, University of Sydney, New South Wales, Australia.
Erick SidartaEijkman Institute for Molecular Biology, Jakarta, Indonesia; School of Life Sciences and Technology, Bandung Institute of Technology, Bandung, Indonesia; Central Blood Center, Indonesian Red Cross, Jakarta, Indonesia; Department of Internal Medicine, Ternate General Hospital, Ternate, Maluku, Indonesia; Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Sydney Medical School, University of Sydney, New South Wales, Australia.
Arkasha SadhewaEijkman Institute for Molecular Biology, Jakarta, Indonesia; School of Life Sciences and Technology, Bandung Institute of Technology, Bandung, Indonesia; Central Blood Center, Indonesian Red Cross, Jakarta, Indonesia; Department of Internal Medicine, Ternate General Hospital, Ternate, Maluku, Indonesia; Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Sydney Medical School, University of Sydney, New South Wales, Australia.
Gludhug Ariyo PurnomoEijkman Institute for Molecular Biology, Jakarta, Indonesia; School of Life Sciences and Technology, Bandung Institute of Technology, Bandung, Indonesia; Central Blood Center, Indonesian Red Cross, Jakarta, Indonesia; Department of Internal Medicine, Ternate General Hospital, Ternate, Maluku, Indonesia; Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Sydney Medical School, University of Sydney, New South Wales, Australia.
Yuyun S M SoedarmonoEijkman Institute for Molecular Biology, Jakarta, Indonesia; School of Life Sciences and Technology, Bandung Institute of Technology, Bandung, Indonesia; Central Blood Center, Indonesian Red Cross, Jakarta, Indonesia; Department of Internal Medicine, Ternate General Hospital, Ternate, Maluku, Indonesia; Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Sydney Medical School, University of Sydney, New South Wales, Australia.
Mochtar Zein PattiihaEijkman Institute for Molecular Biology, Jakarta, Indonesia; School of Life Sciences and Technology, Bandung Institute of Technology, Bandung, Indonesia; Central Blood Center, Indonesian Red Cross, Jakarta, Indonesia; Department of Internal Medicine, Ternate General Hospital, Ternate, Maluku, Indonesia; Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Sydney Medical School, University of Sydney, New South Wales, Australia.
Meta Dewi ThedjaEijkman Institute for Molecular Biology, Jakarta, Indonesia; School of Life Sciences and Technology, Bandung Institute of Technology, Bandung, Indonesia; Central Blood Center, Indonesian Red Cross, Jakarta, Indonesia; Department of Internal Medicine, Ternate General Hospital, Ternate, Maluku, Indonesia; Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Sydney Medical School, University of Sydney, New South Wales, Australia.
Alida R HarahapEijkman Institute for Molecular Biology, Jakarta, Indonesia; School of Life Sciences and Technology, Bandung Institute of Technology, Bandung, Indonesia; Central Blood Center, Indonesian Red Cross, Jakarta, Indonesia; Department of Internal Medicine, Ternate General Hospital, Ternate, Maluku, Indonesia; Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Sydney Medical School, University of Sydney, New South Wales, Australia.
David H MuljonoEijkman Institute for Molecular Biology, Jakarta, Indonesia; School of Life Sciences and Technology, Bandung Institute of Technology, Bandung, Indonesia; Central Blood Center, Indonesian Red Cross, Jakarta, Indonesia; Department of Internal Medicine, Ternate General Hospital, Ternate, Maluku, Indonesia; Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Sydney Medical School, University of Sydney, New South Wales, Australia davidhm@eijkman.go.id.
University of Indonesia · IDEijkman Institute for Molecular Biology · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of hepatitis B virus (HBV) infection has been declining thanks to the universal hepatitis B infant immunization program. Nevertheless, young adults born before the program implementation might have acquired HBV in early childhood or remain susceptible to infection. This study aimed to evaluate hepatitis B epidemiology in asymptomatic young adult population in Ternate, eastern Indonesia. Serum samples of 376 subjects (aged 17-25, mean 19.82 ± 1.69 years; male/female 138/238) were screened for HBV parameters serologically (HBV surface antigen [HBsAg]; its antibody [anti-HBs]; anti-core antigen [anti-HBc]), and molecularly (HBV DNA). HBsAg, anti-HBc, anti-HBs, and HBV DNA prevalence were 15.7%, 36.2%, 24.2%, and 27.9%, respectively, with male predominance. Of all subjects, 13.0% were HBsAg negative with detectable HBV DNA (occult hepatitis B [OHB]), and 56.4% showed negativity for all seromarkers. This population showed high hepatitis B prevalence with substantial occurrence of OHB. However, a high percentage of the population were still susceptible and at risk of HBV infection. This study emphasizes the necessity to improve prevention strategies to screen and manage HBV carriers, including the adoption of catch-up or booster vaccination targeted to young adult populations. Investigations on the roles of host-virus interactions associated with OHB and its implications are warranted.

Indexed as

AdolescentAdultAge FactorsDNA, ViralFemaleHealth SurveysHepatitis BHepatitis B Surface AntigensHumansIndonesiaMalePrevalenceSex FactorsYoung AdultDNA, ViralHepatitis B Surface Antigens

Identifiers

PMID26392157
PMCPMC4674257
OpenAlexW2264498238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.