ArticleThe Plant cell2015
The Circadian Clock Modulates Global Daily Cycles of mRNA Ribosome Loading.
Article in The Plant cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
49 citing papers in PubMed, 91 citations in OpenAlex.
- GCN2 is activated by methyl jasmonate through GCN1 and reactive oxygen species in Arabidopsis thaliana.Scientific reports · 2026Article
- Translational control in plants: from basic mechanisms to environmental and developmental responses.The Plant journal : for cell and molecular biology · 2026Review
- High resolution diel transcriptomes of autotetraploid potato reveal expression and sequence conservation among rhythmic genes.BMC genomics · 2025Article
- Metabolism in Sync: The Circadian Clock, a Central Hub for Light-Driven Chloroplastic and Mitochondrial Entrainment.Plants (Basel, Switzerland) · 2025Review
- Regulatory links between the circadian clock and stress-induced biomolecular condensates.Npj biological timing and sleep · 2025Review
- Circadian Control of Protein Synthesis.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025Review
- Chronotherapy and intervertebral disc degeneration: understanding the role of circadian rhythm in degenerative processes.Frontiers in cell and developmental biology · 2025Review
- Maize inbreds show allelic variation for diel transcription patterns.bioRxiv : the preprint server for biology · 2024Article
- 40S Ribosomal protein S6 kinase integrates daylength perception and growth regulation in Arabidopsis thaliana.Plant physiology · 2024Article
- What, where, and how: Regulation of translation and the translational landscape in plants.The Plant cell · 2024Review
- Circadian regulation of translation.RNA biology · 2024Review
- Legume-rhizobia symbiosis: Translatome analysis.Genetics and molecular biology · 2024Article
- A phospho-dawn of protein modification anticipates light onset in the picoeukaryote Ostreococcus tauri.Journal of experimental botany · 2023Article
- Machine learning estimation of human body time using metabolomic profiling.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- A Miniature Sucrose Gradient for Polysome Profiling.Bio-protocol · 2023Article
- Protein nonadditive expression and solubility contribute to heterosis inFrontiers in plant science · 2023Article
- Keeping development on time: Insights into post-transcriptional mechanisms driving oscillatory gene expression during vertebrate segmentation.Wiley interdisciplinary reviews. RNA · 2023Review
- Variations in Circadian Clock Organization & Function: A Journey from Ancient to Recent.Planta · 2022Review
- Integration of rhythmic metabolome and transcriptome provides insights into the transmission of rhythmic fluctuations and temporal diversity of metabolism in rice.Science China. Life sciences · 2022Article
- Orchestrated translation specializes dinoflagellate metabolism three times per day.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Circadian control of gene expression is well characterized at the transcriptional level, but little is known about diel or circadian control of translation. Genome-wide translation state profiling of mRNAs in Arabidopsis thaliana seedlings grown in long day was performed to estimate ribosome loading per mRNA. The experiments revealed extensive translational regulation of key biological processes. Notably, translation of mRNAs for ribosomal proteins and mitochondrial respiration peaked at night. Central clock mRNAs are among those subject to fluctuations in ribosome loading. There was no consistent phase relationship between peak translation states and peak transcript levels. The overlay of distinct transcriptional and translational cycles can be expected to alter the waveform of the protein synthesis rate. Plants that constitutively overexpress the clock gene CCA1 showed phase shifts in peak translation, with a 6-h delay from midnight to dawn or from noon to evening being particularly common. Moreover, cycles of ribosome loading that were detected under continuous light in the wild type collapsed in the CCA1 overexpressor. Finally, at the transcript level, the CCA1-ox strain adopted a global pattern of transcript abundance that was broadly correlated with the light-dark environment. Altogether, these data demonstrate that gene-specific diel cycles of ribosome loading are controlled in part by the circadian clock.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.