ReviewNature reviews. Gastroenterology & hepatology2015
Practical insights into gluten-free diets.
Review in Nature reviews. Gastroenterology & hepatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 6 syntheses or guidelines pooled it, 173 citations in OpenAlex.
- Relative risk of oral manifestations with celiac disease: a systematic review and meta-analysis.BMC gastroenterology · 2026Pooled it
- European Society for the Study of Coeliac Disease (ESsCD) 2025 Updated Guidelines on the Diagnosis and Management of Coeliac Disease in Adults. Part 2: Management, Follow-Up, and Complex Disease Courses.United European gastroenterology journal · 2026Guideline
- Determination of gluten immunogenic peptides for the management of the treatment adherence of celiac disease: A systematic review.World journal of gastroenterology · 2021Pooled it
- AGA Clinical Practice Update on Diagnosis and Monitoring of Celiac Disease-Changing Utility of Serology and Histologic Measures: Expert Review.Gastroenterology · 2019Guideline
- Use of a Gluten-Free Diet in Schizophrenia: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2018Pooled it
- Are therapeutic diets an emerging additional choice in autism spectrum disorder management?World journal of pediatrics : WJP · 2018Pooled it
- Trial
- Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies.The lancet. Gastroenterology & hepatology · 2017Trial
- The Diagnostic Elimination Diet and Challenge Protocol for Management of Patients with Food Intolerance-Purpose and Development.Nutrients · 2026Article
- Reported Availability, Additional Cost and Use of Methods to Limit Cross-Contact of Gluten-Free Foods in Restaurants in a Canadian Large Urban Centre.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026Article
- Prevalence and Predictors of Persistent Celiac Disease Antibody Positivity During Follow-Up.Digestive diseases and sciences · 2026Article
- Limited Availability and Higher Cost of Gluten-Free Foods Continue in the United Kingdom: A Comparative Follow-Up Over More Than a Decade.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026Article
- Guidelines for the management of coeliac disease: recommendations of the Intestinal Diseases Section of the Polish Society of Gastroenterology.Przeglad gastroenterologiczny · 2026Article
- Clinical, Serologic, and Histologic Characteristics in Screen-Detected and Clinically Diagnosed Celiac Disease Patients.Gastro hep advances · 2026Article
- Celiac disease in children with focus on symptoms and quality of life.Scientific reports · 2025Article
- Management Strategy for Non-Responsive and Refractory Celiac Disease in Adults: A Review Article.Journal of clinical medicine · 2025Review
- Article
- Exploring Challenges Faced by Adults Living With Celiac Disease: A Food Literacy Perspective.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Article
- Dietary assessments in individuals living with coeliac disease: key considerations.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Review
- Burden of coeliac disease in Germany: real-world insights from a large retrospective health insurance claims database analysis.Therapeutic advances in gastroenterology · 2025Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coeliac disease is a global disease, and the only currently available treatment is a gluten-free diet (GFD). Although conceptually simple, the diet changes are substantial and have a profound effect on a patient's life. Untreated coeliac disease is associated with complications, including excess mortality, most of which can be avoided with a strict GFD. However, there are many barriers, including availability, cost and safety of gluten-free foods, and gluten cross-contamination. The GFD can be restrictive in social situations, leading to poor quality of life and, ultimately, nonadherence. As the number of patients with coeliac disease increases worldwide, clinicians need to be aware of the challenges patients face. Heightened awareness by physicians, dietitians and other providers can help maximize successful treatment, improve outcomes, and reduce health-care costs and disease burden. Routine follow-up is necessary to reinforce the need for a GFD, provide social and emotional support, and achieve mucosal healing, leading to reduced risk of complications. Unfortunately, there is wide variation in follow-up practices. The objective of this Review is to increase awareness of the challenges, management and follow-up of patients with coeliac disease to help them achieve GFD adherence and prevent complications whilst preserving their quality of life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.