Evidence map›Paper›PMID 26392035›Full record

ArticleArchives of physical medicine and rehabilitation2016

Site-Specific Transmission of a Floor-Based, High-Frequency, Low-Magnitude Vibration Stimulus in Children With Spastic Cerebral Palsy.

Harshvardhan Singh, Daniel G Whitney, Christopher A Knight, Freeman Miller, Kurt Manal, Paul Kolm, Christopher M Modlesky

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Harshvardhan SinghDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE.
Daniel G WhitneyDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE.
Christopher A KnightDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE.
Freeman MillerDepartment of Orthopedics, Nemours AI duPont Hospital for Children, Wilmington, DE.
Kurt ManalDepartment of Mechanical Engineering, University of Delaware, Newark, DE.
Paul KolmChristiana Care Outcomes Research, Christiana Care Health System, Newark, DE.
Christopher M ModleskyDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE. Electronic address: modlesky@udel.edu.

Funding

Effect of botulinum toxin plus vibration on bone in children with cerebral palsyR15HD071397 · NICHD · UNIVERSITY OF DELAWARE · PI MODLESKY, CHRISTOPHER M · 2012 to 2012
$464k
NICHD NIH HHS HD071397NICHD NIH HHS R15 HD071397
6 · The paper itself

Abstract

objectiveTo determine the degree to which a high-frequency, low-magnitude vibration signal emitted by a floor-based platform transmits to the distal tibia and distal femur of children with spastic cerebral palsy (CP) during standing.

designCross-sectional study.

settingUniversity research laboratory.

participantsChildren with spastic CP who could stand independently (n=18) and typically developing children (n=10) (age range, 4-12y) participated in the study (N=28).

interventionsNot applicable.

main outcome measuresThe vibration signal at the high-frequency, low-magnitude vibration platform (approximately 33Hz and 0.3g), distal tibia, and distal femur was measured using accelerometers. The degree of plantar flexor spasticity was assessed using the Modified Ashworth Scale.

resultsThe high-frequency, low-magnitude vibration signal was greater (P<.001) at the distal tibia than at the platform in children with CP (.36±.06g vs .29±.05g) and controls (.40±.09g vs .24±.07g). Although the vibration signal was also higher at the distal femur (.35±.09g, P<.001) than at the platform in controls, it was lower in children with CP (.20±.07g, P<.001). The degree of spasticity was negatively related to the vibration signal transmitted to the distal tibia (Spearman ρ=-.547) and distal femur (Spearman ρ=-.566) in children with CP (both P<.05).

conclusionsA high-frequency, low-magnitude vibration signal from a floor-based platform was amplified at the distal tibia, attenuated at the distal femur, and inversely related to the degree of muscle spasticity in children with spastic CP. Whether this transmission pattern affects the adaptation of the bones of children with CP to high-frequency, low-magnitude vibration requires further investigation.

Indexed as

AccelerometryVibrationCase-Control StudiesCerebral PalsyChildChild, PreschoolCross-Sectional StudiesFemaleFemurHumansMaleMuscle SpasticityPostureSeverity of Illness IndexTibiaBone and bonesCerebral palsyMuscle spasticityRehabilitationVibration

Identifiers

PMID26392035
PMCPMC4996345

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.