Evidence map›Paper›PMID 26391937›Full record

SynthesisPediatrics2015

Adenotonsillectomy Complications: A Meta-analysis.

Graziela De Luca Canto, Camila Pachêco-Pereira, Secil Aydinoz, Rakesh Bhattacharjee, Hui-Leng Tan, Leila Kheirandish-Gozal, Carlos Flores-Mir, David Gozal

2 registry-linked trialsOpen access · greenAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 61 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 2 pooled it
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03169491 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Caliber of Upper Airway Measured by Acoustic Pharyngometry in Children With Obstructive Sleep Apnea Before and After the Use of Presurgical CPAP and After Adentonsillectomy, and Their Relation With Surgical Complications and Residual Apneas

TypeinterventionalSponsorInstituto Nacional de Enfermedades RespiratoriasRan2016 to 2019Enrolled150ConditionsSleep Apnea, Obstructive, Child, Continuous Positive Airway Pressure, AdenoidectomyArmsContinuous positive airway pressure (CPAP)
NCT04725305 nacompletednot on this mapstarted 2021, after this paper: background citation

BiZact Tonsillectomy

TypeinterventionalSponsorBaylor College of MedicineRan2021 to 2024Enrolled144ConditionsTonsillectomy, Tonsillitis Chronic, Hemorrhage, Postoperative PainArmsBiZact, Standard of care
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 2 syntheses or guidelines pooled it, 204 citations in OpenAlex.

  1. Guideline
  2. Postoperative Bleeding and Associated Utilization following Tonsillectomy in Children.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2017
    Pooled it
  3. Trial
  4. Trial
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  7. Trial
  8. Article
  9. Article
  10. Development and validation of a machine learning model predicting post-tonsillectomy hemorrhage.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  11. Sex-specific effects of surgical duration on peak pain after pediatric adenotonsillectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  12. Article
  13. Disrupted glutamate-gaba balance in children with adenoid hypertrophy:a targeted metabolomic and clinical correlation study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  14. Article
  15. Review
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  17. Observational
  18. Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 5 countries.

Graziela De Luca CantoDepartment of Dentistry, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil; School of Dentistry, Faculty of Medicine and Dentistry, University of Alberta, Alberta, Canada;
Camila Pachêco-PereiraSchool of Dentistry, Faculty of Medicine and Dentistry, University of Alberta, Alberta, Canada;
Secil AydinozGulhane Military Medical Academy, Istanbul, Turkey;
Rakesh BhattacharjeeDivision of Biological Sciences, Department of Pediatrics, Pritzker School of Medicine, University of Chicago, Chicago, Illinois; and.
Hui-Leng TanRoyal Brompton Hospital, Imperial College, London, United Kingdom.
Leila Kheirandish-GozalDivision of Biological Sciences, Department of Pediatrics, Pritzker School of Medicine, University of Chicago, Chicago, Illinois; and.
Carlos Flores-MirSchool of Dentistry, Faculty of Medicine and Dentistry, University of Alberta, Alberta, Canada;
David GozalDivision of Biological Sciences, Department of Pediatrics, Pritzker School of Medicine, University of Chicago, Chicago, Illinois; and dgozal@uchicago.edu.
University of Alberta · CAUniversity of Chicago · USImperial College London · GBNaval Academy · TR

Funding

NEUROCOGNITIVE FUNCTION IN SNORING CHILDRENR01HL065270 · NHLBI · UNIVERSITY OF LOUISVILLE · PI GOZAL, DAVID · 1999 to 2014
$5.0M
NHLBI NIH HHS HL-65270NHLBI NIH HHS R01 HL065270
6 · The paper itself

Abstract

BACKGROUND AND

objectiveComplications after adenotonsillectomy (AT) in children have been extensively studied, but differences between children with and without obstructive sleep apnea (OSA) have not been systematically reported. Our objective was to identify the most frequent complications after AT, and evaluate if differences between children with and without OSA exist.

methodsSeveral electronic databases were searched. A partial gray literature search was undertaken by using Google Scholar. Experts were consulted to identify any missing publications. Studies assessing complications after AT in otherwise healthy children were included. One author collected the required information from the selected articles. A second author crosschecked the collected information and confirmed its accuracy. Most of the selected studies collected information from medical charts.

resultsA total of 1254 studies were initially identified. Only 23 articles remained after a 2-step selection process. The most frequent complication was respiratory compromise (9.4%), followed by secondary hemorrhage (2.6%). Four studies compared postoperative complications in children with and without OSA, and revealed that children with OSA have nearly 5 times more respiratory complications after AT than children without OSA (odds ratio = 4.90; 95% confidence interval: 2.38-10.10). In contrast, children with OSA are less likely to have postoperative bleeding when compared with children without OSA (odds ratio = 0.41; 95% confidence interval: 0.23-0.74).

conclusionsThe most frequent early complications after AT are respiratory compromise and secondary hemorrhage. Based on the current limited evidence, children with OSA appear to have more respiratory complications. Conversely, hemorrhage appears to be more frequent in children without OSA.

Indexed as

AdenoidectomyAdolescentChildChild, PreschoolHumansInfantPostoperative ComplicationsSleep Apnea, ObstructiveTonsillectomy

Identifiers

PMID26391937
PMCPMC9923592
OpenAlexW1615741739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.