ReviewCanadian journal of anaesthesia = Journal canadien d'anesthesie2016
Perioperative stroke.
Review in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.
- Effect of Dual-Site Non-Invasive Brain Stimulation on Upper-Limb Function After Stroke: A Systematic Review and Meta-Analysis.Brain and behavior · 2024Pooled it
- Predicting postoperative complications after pneumonectomy using machine learning: a 10-year study.Annals of medicine · 2025Article
- Effects of Non-Cardiac/Non-neurologic Surgery and Anaesthesia on the CSF Proteome, and Modulation by the APOE Mimetic Peptide CN-105.medRxiv : the preprint server for health sciences · 2025Article
- Elevated risk of perioperative ischemic stroke in noncardiac surgery patients with atrial fibrillation: a retrospective cohort study.BMC anesthesiology · 2025Article
- Association of early perioperative stroke after cardiothoracic surgery with intraoperative regional cerebral oxygenation using near-infrared spectroscopy: an observational cohort study comparing affected versus non-affected hemispheres.Journal of clinical monitoring and computing · 2025Observational
- Patients' perceptions of brain health after surgery: a mixed-methods study of perioperative risk communication in older surgical patients in New Zealand.British journal of anaesthesia · 2025Article
- Development and validation of an interpretable risk prediction model for perioperative ischemic stroke in noncardiac, nonvascular, and nonneurosurgical patients: a retrospective study.Frontiers in physiology · 2025Article
- Development and validation of a machine learning-based model for perioperative stroke prediction in noncardiac, nonvascular, and nonneurosurgical patients.Frontiers in physiology · 2025Article
- Neuraxial anesthesia for non-neurological emergency surgery in a patient with acute ischemic stroke: a case report.International journal of emergency medicine · 2024Article
- Stroke after Cardiac Surgery: A Risk Factor Analysis of 580,117 Patients from UK National Adult Cardiac Surgical Audit Cohort.Journal of personalized medicine · 2024Article
- Perioperative stroke.Nature reviews. Disease primers · 2024Review
- Pre-hospital stroke monitoring past, present, and future: a perspective.Frontiers in neurology · 2024Article
- MicroRNA-323-5p Involved in Dexmedetomidine Preconditioning Impart Neuroprotection.Medicina (Kaunas, Lithuania) · 2023Article
- Myeloid-derived MIF drives RIPK1-mediated cerebromicrovascular endothelial cell death to exacerbate ischemic brain injury.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- CD8Frontiers in cellular neuroscience · 2023Review
- The potential link between obstructive sleep apnea and postoperative neurocognitive disorders: current knowledge and possible mechanisms.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022Review
- A review of perioperative anemia: A modifiable and not so benign risk factor.Journal of family medicine and primary care · 2022Review
- The immunometabolite S-2-hydroxyglutarate exacerbates perioperative ischemic brain injury and cognitive dysfunction by enhancing CD8Journal of neuroinflammation · 2022Article
- Femoral and Lateral Femoral Cutaneous Nerve Block as Anesthesia for High-Risk Intertrochanteric Fracture Repair Patients.Journal of clinical medicine · 2022Article
- Analysis of the Surgical Outcomes in Elderly Patients with Hip Fractures Combined with Hemiplegia.Clinical interventions in aging · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purposePerioperative stroke is associated with significant morbidity and mortality, with an incidence that may be underappreciated. In this review, we examine the significance, pathophysiology, risk factors, and evidence-based recommendations for the prevention and management of perioperative stroke. SOURCE: This is a narrative review based on literature from the PubMed database regarding perioperative stroke across a broad surgical population. The Society for Neuroscience in Anesthesiology and Critical Care recently published evidence-based recommendations for perioperative management of patients at high risk for stroke; these recommendations were analyzed and incorporated into this review. PRINCIPAL
findingsThe incidence of overt perioperative stroke is highest in patients presenting for cardiac and major vascular surgery, although preliminary data suggest that the incidence of covert stroke may be as high as 10% in non-cardiac surgery patients. The pathophysiology of perioperative stroke involves different pathways. Thrombotic stroke can result from increased inflammation and hypercoagulability; cardioembolic stroke can result from disease states such as atrial fibrillation, and tissue hypoxia from anemia can result from the combination of anemia and beta-blockade. Across large-scale database studies, common risk factors for perioperative stroke include advanced age, history of cerebrovascular disease, ischemic heart disease, congestive heart failure, atrial fibrillation, and renal disease. Recommendations for prevention and management of perioperative stroke are evolving, though further work is needed to clarify the role of proposed modifiable risk factors such as perioperative anticoagulation, antiplatelet therapy, appropriate transfusion thresholds, and perioperative beta-blockade.
conclusionsPerioperative stroke carries a significant clinical burden. The incidence of perioperative stroke may be higher than previously recognized, and there are diverse pathophysiologic mechanisms. There are many opportunities for further investigation of the pathophysiology, prevention, and management of perioperative stroke.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.