Trial reportTrials2015
Interactive web-based lifestyle intervention and metabolic syndrome: findings from the Red Ruby (a randomized controlled trial).
Trial report in Trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.
What it found
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Who cites it
24 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- A systematic review of influences on engagement with remote health interventions targeting weight management for individuals living with excess weight.International journal of obesity (2005) · 2025Pooled it
- Automated lifestyle interventions and weight loss: a systematic review of randomized controlled trials.International journal of obesity (2005) · 2025Pooled it
- Education-based, lifestyle intervention programs with unsupervised exercise improve outcomes in adults with metabolic syndrome. A systematic review and meta-analysis.Reviews in endocrine & metabolic disorders · 2021Pooled it
- A Technology-Mediated Interventional Approach to the Prevention of Metabolic Syndrome: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- The effect of community-based programs on diabetes prevention in low- and middle-income countries: a systematic review and meta-analysis.Globalization and health · 2019Pooled it
- Trial
- Intervention to Improve Menstrual Health Among Adolescent Girls Based on the Theory of Planned Behavior in Iran: A Cluster-randomized Controlled Trial.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2022Trial
- The effectiveness of social media and in-person interventions for low back pain conditions in nursing personnel (SMILE).Nursing open · 2021Trial
- The Effect of a Theory of Planned Behavior-based Educational Intervention on Sexual and Reproductive Health in Iranian Adolescent Girls: A Randomized Controlled Trial.Journal of research in health sciences · 2017Trial
- An interactive web-based intervention on nutritional status, physical activity and health-related quality of life in patient with metabolic syndrome: a randomized-controlled trial (The Red Ruby Study).Nutrition & diabetes · 2017Trial
- Article
- Perceived Neighborhood Trust, Health Behaviors, and Metabolic Syndrome Among Middle-Aged and Older Chinese Adults: A Cross-Sectional Study.Behavioral sciences (Basel, Switzerland) · 2026Article
- Exploring Education Interventions for Stroke Prevention Among Adults and Older Individuals: A Scoping Review.Health science reports · 2024Article
- Lifestyle patterns, nutritional, and metabolic syndrome determinants in a sample of the older Iranian population.BMC geriatrics · 2024Article
- Article
- Effectiveness of Information and Communications Technology-Based Interventions for Obesity and Metabolic Syndrome.Journal of obesity & metabolic syndrome · 2022Article
- Effect of a Community Gerontology Program on the Control of Metabolic Syndrome in Mexican Older Adults.Healthcare (Basel, Switzerland) · 2022Article
- Gender Differences of Health Behaviors in the Risk of Metabolic Syndrome for Middle-Aged Adults: A National Cross-Sectional Study in South Korea.International journal of environmental research and public health · 2021Article
- The Utility of Artificial Neural Networks for the Non-Invasive Prediction of Metabolic Syndrome Based on Personal Characteristics.International journal of environmental research and public health · 2020Article
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMetabolic syndrome is a growing public health problem worldwide. Several interventions have been proposed to specifically target the problem. This study evaluated the effectiveness of an interactive web-based lifestyle for management of metabolic syndrome.
methodsThis randomized controlled trial was conducted from June through August 2012 in Tehran, Iran. Participants were individuals with metabolic syndrome who had registered on the study website. Interested eligible participants were invited for a free clinic visit and clinical assessment. They were randomly assigned to the intervention (n =80) or control (n = 80) group. The intervention group received an interactive web-based program called the Healthy Heart Profile and were followed for 6 months. The control group received general information on metabolic syndrome. Anthropometric measures, glycemic status, and lipid profile were evaluated at baseline, and at 3- and 6-month follow-up assessments. Metabolic syndrome was defined according to The National Cholesterol Education Program Adult Treatment Panel (ATP) III report except for waist circumference, which was modified to ≥90 cm for both genders for the Iranian population.
resultsIn total, 1,437 individuals registered on the study website. The mean age of participants was 44.2 years (SD = 10.0). There were no significant differences between the intervention and control groups on any baseline variable except that participants in the intervention group recorded higher levels of LDL. The results showed a decrease in metabolic syndrome in both groups. These reductions were significantly greater in the intervention group at the 3- and 6-month follow-ups. The intervention group showed significantly greater decreases (P < 0.05) over the control group for, respectively, systolic blood pressure (3-month: -10 versus -6 mmHg; 6-month: -11 versus -8 mmHg), diastolic blood pressure (3-month: -10 versus -4 mmHg; 6-month: -11 versus -6 mmHg), weight (3-month: -2 versus -1 kg; 6-month: -4 versus -1 kg), body mass index (3-month: -0.5 versus -0.2 kg/m(2); 6-month: -1.1 versus -0.4 kg/m(2)) and improvement in HDL (3-month: 2 versus 0.64 mg/dl; 6-month: 6 versus 4 mg/dl).
conclusionThe findings suggest that the web-based interactive program was beneficial for individuals with metabolic syndrome. Comprehensive interactive web-based prevention programs are promising to help involve patients in improving management of metabolic syndrome and adopting a healthy lifestyle.
trial registrationIRCT201111198132N1 . Registered 27 May 2013.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.