Evidence map›Paper›PMID 26390356›Full record

ReviewAdvanced materials (Deerfield Beach, Fla.)2016

Layer-by-Layer Assemblies for Cancer Treatment and Diagnosis.

Xi Qiu Liu, Catherine Picart

Abstract readReview
In one paragraph

Review in Advanced materials (Deerfield Beach, Fla.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
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  16. Article
  17. Engineering nanolayered particles for modular drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xi Qiu LiuUMR CNRS/INPG 5628 (LMGP), 3 parvis Louis Néel, 38016, Grenoble, France.
Catherine PicartUMR CNRS/INPG 5628 (LMGP), 3 parvis Louis Néel, 38016, Grenoble, France.

Funding

European Research Council 259370
6 · The paper itself

Abstract

The layer-by-layer (LbL) technique was introduced in the early 1990s. Since then, it has undergone a series of technological developments, making it possible to engineer various theranostic platforms, such as films and capsules, with precise control at the nanometer and micrometer scales. Recent progress in the applications of LbL assemblies in the field of cancer therapy, diagnosis, and fundamental biological study are highlighted here. The potential of LbL-based systems as drug carriers is discussed, especially with regard to the engineering of innovative stimuli-responsive systems, and their advantageous multifunctionality in the development of new therapeutic tools. Then, the diagnostic functions of LbL assemblies are illustrated for detection and capture of rare cancer cells. Finally, LbL-mimicking extracellular environments demonstrate the emerging potential for the study of cancer cell behavior in vitro. The advantages of LbL systems, important challenges that need to be overcome, and future perspectives in clinical practice are then highlighted.

Indexed as

AnimalsBiosensing TechniquesCapsulesDoxorubicinDrug CarriersDrug CompoundingHumansHydrogen-Ion ConcentrationLiposomesNanoparticlesNanotechnologyNeoplasmsPolymersRatsRNA, Small InterferingTemperatureCapsulesDoxorubicinDrug CarriersLiposomesPolymersRNA, Small Interferingcancercellular behaviorsdiagnosisdrug deliverylayer-by-layer

Identifiers

PMID26390356
PMCPMC5024746

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.