Evidence map›Paper›PMID 26390295›Full record

ArticlePloS one2015

Recording of Influenza-Like Illness in UK Primary Care 1995-2013: Cohort Study.

Pia Hardelid, Greta Rait, Ruth Gilbert, Irene Petersen

Abstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Factors predicting amoxicillin prescribing in primary care among children: a cohort study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2022
    Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Influenza-Like Illness in Travelers to the Developing World.The American journal of tropical medicine and hygiene · 2018
    Observational
  8. Article
  9. Long-lasting cough in an adult German population: incidence, symptoms, and related pathogens.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pia HardelidPopulation, Policy and Practice Programme, University College London Institute of Child Health, London, United Kingdom; Research Department of Primary Care and Population Health, University College London, London, United Kingdom.
Greta RaitPRIMENT Clinical Trials Unit, Research Department of Primary Care and Population Health, University College London, London, United Kingdom.
Ruth GilbertPopulation, Policy and Practice Programme, University College London Institute of Child Health, London, United Kingdom.
Irene PetersenResearch Department of Primary Care and Population Health, University College London, London, United Kingdom; Department of Clinical Epidemiology, Aarhus University, Aarhus, Denmark.

Funding

Department of Health PDF-2013-06-004Medical Research Council MR/K006584/1
6 · The paper itself

Abstract

backgroundThere is a lack of recent studies examining recording of influenza-like illness (ILI) in primary care in the UK over time and according to population characteristics. Our aim was to determine time trends and socio-demographic patterns of ILI recorded consultations in primary care.

methodsWe used The Health Improvement Network (THIN) UK primary care database and extracted data on all ILI consultations between 1995 and 2013. We estimated ILI recorded consultation rates per 100,000 person-weeks (pw) by age, gender, deprivation and winter season. Negative binomial regression models were used to examine time trends and the effect of socio-demographic characteristics. Trends in ILI recorded consultations were compared to trends in consultations with less specific symptoms (cough or fever) recorded.

resultsThe study involved 7,682,908 individuals in 542 general practices. The ILI consultation rate decreased from 32.5/100,000 pw (95% confidence interval (CI) 32.1, 32.9) in 1995-98 to 15.5/100,000 pw (95% CI 15.4, 15.7) by 2010-13. The decrease occurred prior to 2002/3, and rates have remained largely stable since then. Declines were evident in all age groups. In comparison, cough or fever consultation rates increased from 169.4/100,000 pw (95% CI 168.6, 170.3) in 1995-98 to 237.7/100,000 pw (95% CI 237.2, 238.2) in 2010-13. ILI consultation rates were highest among individuals aged 15-44 years, higher in women than men, and in individuals from deprived areas.

conclusionThere is substantial variation in ILI recorded consultations over time and by population socio-demographic characteristics, most likely reflecting changing recording behaviour by GPs. These results highlight the difficulties in using coded information from electronic primary care records to measure the severity of influenza epidemics across time and assess the relative burden of ILI in different population subgroups.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolCohort StudiesCoughDatabases, FactualEpidemicsFemaleFeverGeneral PracticeHumansInfantInfluenza, Human

Identifiers

PMID26390295
PMCPMC4577110

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.