ArticleJournal of abnormal psychology2015
Elevated striatal reactivity across monetary and social rewards in bipolar I disorder.
Article in Journal of abnormal psychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Neural correlates of impulsivity in bipolar disorder: A systematic review and clinical implications.Neuroscience and biobehavioral reviews · 2023Pooled it
- Neural reward circuit dysfunction as a risk factor for bipolar spectrum disorders and substance use disorders: A review and integration.Clinical psychology review · 2021Pooled it
- Temporal Dynamics of Reward Dysfunction in Psychiatric Disorders: Memory-Derived Value, Incentive Salience, Hedonic Impact, and Value Updating.Biological psychiatry global open science · 2026Review
- Sex-specific associations of episode type in bipolar I disorder with neuro-metabolic lateralization of the cortico-striatal-cerebellar (CSC) circuit.BMC psychiatry · 2025Article
- A transdiagnostic approach to understanding neural responsivity to reward and its links to social motivation.Schizophrenia research. Cognition · 2025Article
- Personally valued voices engage reward-motivated behaviour and brain responses.Social cognitive and affective neuroscience · 2025Article
- Neural markers of mania that distinguish inpatient adolescents with bipolar disorder from those with other psychopathology.Psychiatry research · 2024Article
- Comparing adaptive coding of reward in bipolar I disorder and schizophrenia.Human brain mapping · 2023Article
- Relationships between Personality Traits and Brain Gray Matter Are Different in Risky and Non-risky Drivers.Behavioural neurology · 2022Article
- Schizophrenia and bipolar disorder are associated with opposite brain reward anticipation-associated response.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Article
- Proximate and Ultimate Perspectives on Romantic Love.Frontiers in psychology · 2021Review
- No group differences in Traditional Economics Measures of loss aversion and framing effects in bipolar I disorder.PloS one · 2021Article
- Resting-state functional connectivity of neural circuits associated with primary and secondary rewards in patients with bipolar disorder.Social cognitive and affective neuroscience · 2020Article
- Understanding and Taking Stock of Positive Emotion Disturbance.Social and personality psychology compass · 2020Article
- Neurophysiological correlates of cognitive control and approach motivation abnormalities in adolescent bipolar disorders.Cognitive, affective & behavioral neuroscience · 2019Article
- Chronotype and Mental Health: Recent Advances.Current psychiatry reports · 2018Review
- Lack of emotional gaze preferences using eye-tracking in remitted bipolar I disorder.International journal of bipolar disorders · 2018Article
- Presentation and Neurobiology of Anhedonia in Mood Disorders: Commonalities and Distinctions.Current psychiatry reports · 2018Review
- Differentiation of Transformed Bipolar Disorder From Unipolar Depression by Resting-State Functional Connectivity Within Reward Circuit.Frontiers in psychology · 2018Article
- Disrupted cortico-limbic connectivity during reward processing in remitted bipolar I disorder.Bipolar disorders · 2017Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Bipolar disorder (BD) is associated with increased reactivity to rewards and heightened positive affectivity. It is less clear to what extent this heightened reward sensitivity is evident across contexts and what the associated neural mechanisms might be. The present investigation used both a monetary and social incentive delay task among adults with remitted BD Type I (n = 24) and a healthy nonpsychiatric control group (HC; n = 25) using fMRI. Both whole-brain and region-of-interest analyses revealed elevated reactivity to reward receipt in the striatum, a region implicated in incentive sensitivity, in the BD group. Post hoc analyses revealed that greater striatal reactivity to reward receipt, across monetary and social reward tasks, predicted decreased self-reported positive affect when anticipating subsequent rewards in the HC but not in the BD group. Results point toward elevated striatal reactivity to reward receipt as a potential neural mechanism of persistent reward pursuit in BD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.