Evidence map›Paper›PMID 26390180›Full record

ArticleMagnetic resonance in medicine2016

Variable flip angle 3D-GRASE for high resolution fMRI at 7 tesla.

Valentin G Kemper, Federico De Martino, Essa Yacoub, Rainer Goebel

Abstract readEvaluation Study
In one paragraph

Article in Magnetic resonance in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Layer-dependent functional connectivity methods.Progress in neurobiology · 2021
    Review
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  8. Review
  9. Controlling TMagnetic resonance in medicine · 2018
    Article
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  11. Visually-Driven Maps in Area 3b.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Valentin G KemperDepartment of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, MD Maastricht, The Netherlands.
Federico De MartinoDepartment of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, MD Maastricht, The Netherlands.
Essa YacoubCenter for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Rainer GoebelDepartment of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, MD Maastricht, The Netherlands.

Funding

NMR Imaging and SpectroscopyP41EB015894 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2017
$8.4M
NIBIB NIH HHS P41 EB015894
6 · The paper itself

Abstract

purposeTo evaluate the use of variable flip angle refocusing pulse trains in single-shot three-dimensional gradient and spin-echo (3D-GRASE) to reduce blurring and increase the spatial coverage for high spatial resolution T2 -weighted functional MRI at 7 Tesla.

methodsVariable flip angle refocusing schemes in 3D-GRASE were calculated based on extended phase graph theory. The blurring along the slice (partition) direction was evaluated in simulations, as well as phantom and in vivo experiments. Furthermore, temporal stability and functional sensitivity at 0.8 mm isotropic resolution were assessed.

resultsVariable flip angle refocusing schemes yielded significantly reduced blurring compared with conventional refocusing schemes, with the full width at half maximum being approximately 30-40% narrower. Simultaneously, spatial coverage could be increased by 80%. The temporal signal-to-noise ratio was slightly reduced, but functional sensitivity was largely maintained due to increased functional contrast in the variable flip angle acquisitions. Signal-to-noise ratio and functional sensitivity were reduced more strongly in areas with insufficient radiofrequency transmission indicating higher sensitivity to experimental imperfections.

conclusionVariable flip angle refocusing schemes increase usability of 3D-GRASE for high-resolution functional MRI by reducing blurring and allowing increased spatial coverage. Magn Reson Med 76:897-904, 2016. © 2015 Wiley Periodicals, Inc.

Indexed as

Signal Processing, Computer-AssistedAlgorithmsBrainBrain MappingEvoked PotentialsHumansImage EnhancementImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingReproducibility of ResultsSensitivity and Specificity3D-GRASE7Thigh-resolution fMRIpoint-spread functionT2 weighted fMRIvariable flip angle

Identifiers

PMID26390180
PMCPMC4801698

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.