Evidence map›Paper›PMID 26389988›Full record

ArticleJournal of the American Geriatrics Society2015

Age-Related Differences in Sleep-Wake Symptoms of Adults Undergoing Polysomnography.

Carlos A Vaz Fragoso, Peter H Van Ness, Katy L B Araujo, Lynne P Iannone, Henry Klar Yaggi

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of the American Geriatrics Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Self-reported and actigraphic short sleep duration in older adults.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  7. Article
  8. Predictors of Insomnia Severity Index Profiles in United States Veterans With Obstructive Sleep Apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Article
  9. Article
  10. Insomnia in Community-Living Persons with Advanced Age.Journal of the American Geriatrics Society · 2018
    Article
  11. Impact of Sleep-Disordered Breathing Treatment on Patient Reported Outcomes in a Clinic-Based Cohort of Hypertensive Patients.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2016
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Carlos A Vaz FragosoClinical Epidemiology Research Center, Veterans Affairs Connecticut, West Haven, Connecticut.
Peter H Van NessDepartment of Medicine, School of Medicine, Yale University, New Haven, Connecticut.
Katy L B AraujoDepartment of Medicine, School of Medicine, Yale University, New Haven, Connecticut.
Lynne P IannoneClinical Epidemiology Research Center, Veterans Affairs Connecticut, West Haven, Connecticut.
Henry Klar YaggiClinical Epidemiology Research Center, Veterans Affairs Connecticut, West Haven, Connecticut.
Yale University · US

Funding

Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Albert C Shaw · 2002 to 2026
$37.9M
Respiratory Impairment in Aging PopulationsI01CX000927 · VA · VA CONNECTICUT HEALTHCARE SYSTEM · PI FRAGOSO, CARLOS A. VAZ · 2014 to 2016
–
CSRD VA I01 CX000927NIA NIH HHS P30 AG021342
6 · The paper itself

Abstract

objectivesTo evaluate age-related differences in sleep-wake symptoms.

designCross-sectional.

settingTechnologist-attended, laboratory-based polysomnography (PSG).

participantsCommunity-dwelling adults aged 20 to 89 (N = 201): 52 aged 18 to 39, 72 aged 40 to 59, and 77 aged 60 and older. MEASUREMENTS: Medical burden (Charlson Comorbidity Index, medications, health status), PSG-defined sleep disorders (sleep-disordered breathing (SDB), sleep-associated hypoxemia, periodic limb movements in sleep (PLMS)), sleep-wake symptoms (Epworth Sleepiness Scale (ESS), Insomnia Severity Index (ISI), fatigue (Facit-F Scale)).

resultsMedical burden increased significantly with age (Charlson Comorbidity Index and number of medications, P < .001; health status, P = .005). Severity of sleep disorders also increased significantly with age (SDB and hypoxemia, P < .001; PLMS, P = .008). Conversely, sleep-wake symptoms decreased with age (daytime drowsiness (ESS ≥ 10), P = .02; insomnia (ISI ≥ 8), P = .04; fatigue, P < .001). In adjusted models, a 1-year increase in age was significantly associated with a 4% decrease in the odds of having daytime drowsiness (odds ratio (OR) = 0.96, 95% confidence interval (CI) = 0.93-0.98). Similarly, but only in those with mild SDB, a 1-year increase in age was significantly associated with a 5% decrease in the odds of having insomnia (OR = 0.95, 95% CI = 0.92-0.99).

conclusionOlder age was characterized by less-severe sleep-wake symptoms (daytime drowsiness, insomnia, fatigue), despite an age-related increase in disease severity (medical burden, sleep disorders). Because the increase in disease severity included well-established risk factors for having sleep-wake symptoms, the age-related decrease in sleep-wake symptoms may reflect a decrease in symptom awareness.

Indexed as

PolysomnographyAdolescentAdultAge FactorsCross-Sectional StudiesFemaleHumansMaleMiddle AgedSleep Wake DisordersYoung Adultdriving capacityperiodic limb movementssleep-disordered breathingsleep-wake symptoms

Identifiers

PMID26389988
PMCPMC5287358
OpenAlexW1948574911

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.