Trial reportNutrients2015
Dietary Sources of Vitamin B-12 and Their Association with Vitamin B-12 Status Markers in Healthy Older Adults in the B-PROOF Study.
Trial report in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 59 citations in OpenAlex.
- Cyano-B12 or Whey Powder with Endogenous Hydroxo-B12 for Supplementation in B12 Deficient Lactovegetarians.Nutrients · 2019Trial
- Folate and Vitamin BNutrients · 2016Trial
- Effects of Recommended Supplementation and Mediterranean Diet Adherence on Post-Metabolic Bariatric Surgery Outcomes.Biomedicines · 2026Article
- Dietary intake adequacy among Iranian older adults: evidence from national household survey data and two population-based cohorts.Frontiers in nutrition · 2026Article
- A simple, fast and inexpensive approach using E. coli to detect and estimate vitamin B12 content in microbial extracts.Biology open · 2025Article
- Correlates of serum holo-Transcobalamin in the elderly general population.European journal of nutrition · 2025Article
- The clinical utility and cost-effectiveness of routine vitamin BThe South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025Article
- Minerals and Trace Elements: Key Protectors of Skin Health and Defenders against Skin Disorders.Current medicinal chemistry · 2025Review
- Prevalence of vitamin B 12 deficiency and associated factors among primary school children: North East Ethiopia: multicenter cross-sectional study.Journal of health, population, and nutrition · 2024Article
- The relationship of sperm DNA integrity with serum vitamin levels (folate and cobalamin) and food consumption in infertile men.Clinical and experimental reproductive medicine · 2023Article
- Vitamin B-12 Intake from Dairy but Not Meat Is Associated with Decreased Risk of Low Vitamin B-12 Status and Deficiency in Older Adults from Quebec, Canada.The Journal of nutrition · 2022Article
- Plants, Plants, and More Plants: Plant-Derived Nutrients and Their Protective Roles in Cognitive Function, Alzheimer's Disease, and Other Dementias.Medicina (Kaunas, Lithuania) · 2022Review
- Association between Intake of Total Dairy and Individual Dairy Foods and Markers of Folate, Vitamin BNutrients · 2022Article
- Age-dependent changes in fat- and water-soluble vitamins-National Health and Nutrition Examination Surveys study.Frontiers in medicine · 2022Article
- Changes in micronutrient intake and factors associated with this change among older Australian men: the Concord Health and Ageing in Men Project.Public health nutrition · 2021Article
- Testing and Prescribing Vitamin B12 in Swiss General Practice: A Survey among Physicians.Nutrients · 2021Article
- Perspective: Practical Approach to Preventing Subclinical B12 Deficiency in Elderly Population.Nutrients · 2021Review
- Dietary Interventions for Treatment of Chronic Pain: Oxidative Stress and Inflammation.Pain and therapy · 2020Review
- Relationship between metformin use and vitamin BJournal of diabetes investigation · 2020Article
- Predictors of serum cobalamin and its association with homocysteine in community-dwelling older adults.European journal of clinical nutrition · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Low vitamin B-12 concentrations are frequently observed among older adults. Malabsorption is hypothesized to be an important cause of vitamin B-12 inadequacy, but serum vitamin B-12 may also be differently affected by vitamin B-12 intake depending on food source. We examined associations between dietary sources of vitamin B-12 (meat, fish and shellfish, eggs, dairy) and serum vitamin B-12, using cross-sectional data of 600 Dutch community-dwelling adults (≥65 years). Dietary intake was assessed with a validated food frequency questionnaire. Vitamin B-12 concentrations were measured in serum. Associations were studied over tertiles of vitamin B-12 intake using P for trend, by calculating prevalence ratios (PRs), and splines. Whereas men had significantly higher vitamin B-12 intakes than women (median (25th-75th percentile): 4.18 (3.29-5.38) versus 3.47 (2.64-4.40) μg/day), serum vitamin B-12 did not differ between the two sexes (mean ± standard deviation (SD): 275 ± 104 pmol/L versus 290 ± 113 pmol/L). Higher intakes of dairy, meat, and fish and shellfish were significantly associated with higher serum vitamin B-12 concentrations, where meat and dairy-predominantly milk were the most potent sources. Egg intake did not significantly contribute to higher serum vitamin B-12 concentrations. Thus, dairy and meat were the most important contributors to serum vitamin B-12, followed by fish and shellfish.
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