Evidence map›Paper›PMID 26389921›Full record

ArticleMarine drugs2015

Nitrogen-Containing Diterpenoids, Sesquiterpenoids, and Nor-Diterpenoids from Cespitularia taeniata.

Shih-Sheng Wang, Yuan-Bin Cheng, Yu-Chi Lin, Chia-Ching Liaw, Jiun-Yang Chang, Yao-Haur Kuo, Ya-Ching Shen

Abstract read
In one paragraph

Article in Marine drugs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shih-Sheng WangSchool of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan. aska@newbellus.com.tw.
Yuan-Bin ChengGraduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan. jmb@kmu.edu.tw.
Yu-Chi LinSchool of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan. z10108042@email.ncku.edu.tw.
Chia-Ching LiawSchool of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan. biogodas@hotmail.com.
Jiun-Yang ChangDepartment of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan. dryang323@gmail.com.
Yao-Haur KuoNational Research Institute of Chinese Medicine, Taipei 112, Taiwan. kuoyh@nricm.edu.tw.
Ya-Ching ShenSchool of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan. ycshen@ntu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two new nitrogen-containing verticillene diterpenoids, cespilamides A and B (1 and 2), three new nitrogen-containing sesquiterpenoids, cespilamides C-E (3-5), and five new norverticillene and verticillene diterpenoids, cespitaenins A-E (6-10), were isolated from the Taiwanese soft coral Cespitularia taeniata. Compound 1 possesses an unusual oxazo ring system at C-10 while compound 2 displays an unprecedented C-C bond cleavage between C-10 and C-11 with an N-ethylphenyl group at C-10. Biogenetic pathways of 1 and 2 are proposed. The absolute configuration of 1 was confirmed by Mosher's method and molecular mechanics calculations (MM2). The cytotoxicities of compounds 1-10 were evaluated against a small panel of human cancer cell lines.

Indexed as

AnimalsAnthozoaDiterpenesMolecular StructureSesquiterpenesDiterpenesSesquiterpenesCespitularia taeniatacytotoxicityverticillene diterpenoids

Identifiers

PMID26389921
PMCPMC4584355

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.