ReviewInternational journal of molecular sciences2015
Digital Microfluidics for Manipulation and Analysis of a Single Cell.
Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Decoding Cellular Heterogeneity with Microfluidic Single-Cell Secretion Analysis Tools.ACS omega · 2026Review
- Advances in Platelet-Dysfunction Diagnostic Technologies.Biomolecules · 2024Review
- Micro/nanorobots for gastrointestinal tract.Frontiers in chemistry · 2024Review
- Digital microfluidics-engaged automated enzymatic degradation and synthesis of oligosaccharides.Frontiers in bioengineering and biotechnology · 2023Article
- Lab-on-a-Chip Platforms for Airborne Particulate Matter Applications: A Review of Current Perspectives.Biosensors · 2022Review
- High-Throughput Cell Trapping in the Dentate Spiral Microfluidic Channel.Micromachines · 2021Article
- Recent advances in critical nodes of embryo engineering technology.Theranostics · 2021Review
- Cell-free biology using remote-controlled digital microfluidics for individual droplet control.RSC advances · 2020Article
- Enhanced sample filling and discretization in thermoplastic 2D microwell arrays using asymmetric contact angles.Biomicrofluidics · 2020Article
- A Potential Application of Triangular Microwells to Entrap Single Cancer Cells: A Canine Cutaneous Mast Cell Tumor Model.Micromachines · 2019Article
- A fluorescent microbead-based microfluidic immunoassay chip for immune cell cytokine secretion quantification.Lab on a chip · 2018Article
- High-throughput multiplexed fluorescence-activated droplet sorting.Microsystems & nanoengineering · 2018Article
- Controlled droplet discretization and manipulation using membrane displacement traps.Lab on a chip · 2017Article
- Review
- Rapid, chemical-free breaking of microfluidic emulsions with a hand-held antistatic gun.Biomicrofluidics · 2017Article
- Single cell biology beyond the era of antibodies: relevance, challenges, and promises in biomedical research.Cellular and molecular life sciences : CMLS · 2017Review
- Opto-Microfluidic Immunosensors: From Colorimetric to Plasmonic.Micromachines · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The basic structural and functional unit of a living organism is a single cell. To understand the variability and to improve the biomedical requirement of a single cell, its analysis has become a key technique in biological and biomedical research. With a physical boundary of microchannels and microstructures, single cells are efficiently captured and analyzed, whereas electric forces sort and position single cells. Various microfluidic techniques have been exploited to manipulate single cells through hydrodynamic and electric forces. Digital microfluidics (DMF), the manipulation of individual droplets holding minute reagents and cells of interest by electric forces, has received more attention recently. Because of ease of fabrication, compactness and prospective automation, DMF has become a powerful approach for biological application. We review recent developments of various microfluidic chips for analysis of a single cell and for efficient genetic screening. In addition, perspectives to develop analysis of single cells based on DMF and emerging functionality with high throughput are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.