ArticlePediatric research2016
Impaired cardiac autonomic nervous system function is associated with pediatric hypertension independent of adiposity.
Article in Pediatric research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Who cites it
17 citing papers in PubMed, 24 citations in OpenAlex.
- Ambulatory blood pressure variability in prediction of target organ injury: the SHIP AHOY study.Pediatric nephrology (Berlin, Germany) · 2026Article
- Early-life adversity before age 5 is associated with reduced cardiometabolic health characterized by increased arterial stiffness and inflammation in adolescence.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Article
- Enhanced smart commuting with artificial intelligence for intelligent health and safety monitoring in school buses.Scientific reports · 2026Article
- Post-adoption experiences of discrimination moderated by sleep quality are associated with depressive symptoms in previously institutionalized youth over and above deprivation-induced depression risk.Development and psychopathology · 2024Article
- Predictors of Cardiac Autonomic Dysfunction in Obesity-Related Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024Article
- A Recreational Swimming Intervention during the Whole School Year Improves Fitness and Cardiometabolic Risk in Children and Adolescents with Overweight and Obesity.International journal of environmental research and public health · 2022Article
- Increasing Vegetable Diversity Consumption Impacts the Sympathetic Nervous System Activity in School-Aged Children.Nutrients · 2021Article
- Obesity, metabolic syndrome, and primary hypertension.Pediatric nephrology (Berlin, Germany) · 2021Article
- Haemodynamics of Hypertension in Children.Current hypertension reports · 2020Review
- Parental Renovascular Hypertension-Induced Autonomic Dysfunction in Male Offspring Is Improved by Prenatal or Postnatal Treatment With Hydrogen Sulfide.Frontiers in physiology · 2019Article
- Early Life Adversity with Height Stunting Is Associated with Cardiometabolic Risk in Adolescents Independent of Body Mass Index.The Journal of pediatrics · 2018Article
- Relationships of Anxiety and Depression with Cardiovascular Health in Youth with Normal Weight to Severe Obesity.The Journal of pediatrics · 2018Article
- Cardiometabolic risk factors in treatment-seeking youth versus population youth with obesity.Obesity science & practice · 2018Article
- Determination of Bilateral Symmetry of Carotid Artery Structure and Function in Children and Adolescents.Journal of vascular diagnostics and interventions · 2017Article
- Antenatal steroid exposure and heart rate variability in adolescents born with very low birth weight.Pediatric research · 2017Article
- Utility of Body Mass Index in Identifying Excess Adiposity in Youth Across the Obesity Spectrum.The Journal of pediatrics · 2016Article
- Effect of obesity on sleep quality, anthropometric and autonomic parameters in adolescent.Sleep science (Sao Paulo, Brazil)Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundWe examined whether sympathetic nervous system activity influences hypertension status and systolic blood pressure (SBP) independent of adiposity in youth ranging from normal-weight to severe obesity.
methodsWe examined the association of heart rate variability (HRV) with hypertension status and SBP among youth (6-18 y old; n = 188; 103 female). Seated SBP was measured using an automated cuff. Prehypertension (SBP percentile ≥ 90th to <95th) and hypertension (SBP percentile ≥ 95th) were defined by age-, sex-, and height-norms. Autonomic nervous system activity was measured using HRV via SphygmoCor MM3 system and analyzed for time- and frequency-domains. Total body fat was measured via dual-energy X-ray absorptiometry.
resultsLogistic regression models demonstrated lower values in each time-domain HRV measure and larger low-frequency (LF):high-frequency (HF) ratio to be significantly associated with higher odds of being prehypertensive/hypertensive (11-47% higher odds) independent of total body fat (P < 0.05). In linear regression analysis, lower time-domain, but not frequency-domain, HRV measures were significantly associated with higher SBP independent of total body fat (P < 0.05).
conclusionThese data suggest that impaired cardiac autonomic nervous system function, at rest, is associated with higher odds of being prehypertensive/hypertensive and higher SBP which may be independent of adiposity in youth.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.